Evidence map›Paper›PMID 38105961›Full record

ArticlebioRxiv : the preprint server for biology2023

A semi-automated cell tracking protocol for quantitative analyses of neutrophil swarming to sterile and

Sashank Lekkala, Youliang Ren, Jason Weeks, Kevin Lee, Allie Jia Hui Tay, Bei Liu, Thomas Xue, Joshua Rainbolt, Chao Xie, Edward M Schwarz and 1 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Sashank LekkalaDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.ORCID 0000-0001-6638-9029
Youliang RenCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
Jason WeeksCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
Kevin LeeDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Allie Jia Hui TayDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Bei LiuCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
Thomas XueDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Joshua RainboltCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.
Chao XieCenter for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY, USA.ORCID 0000-0001-6197-2506
Edward M SchwarzDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.ORCID 0000-0002-4854-9698
Shu-Chi A YehDepartment of Biomedical Engineering, University of Rochester, Rochester, NY, USA.ORCID 0000-0003-1898-9665
University of Rochester Medical Center · US

Funding

Project 2: Defining the Protective vs. Susceptible Immune Proteome of S. aureus OsteomyelitisP50AR072000 · NIAMS · UNIVERSITY OF ROCHESTER · PI Benjamin L Miller · 2017 to 2026
$13.6M
Rochester Resource-Based Center for Bone, Muscle and Orthopaedic Research (ROCSTARR) (Overall Application)P30AR069655 · NIAMS · UNIVERSITY OF ROCHESTER · PI Edward M. Schwarz · 2016 to 2026
$7.8M
Quantifying the Race for the Surface via IV-MLSMR21AR081050 · NIAMS · UNIVERSITY OF ROCHESTER · PI SCHWARZ, EDWARD M., XIE, CHAO · 2022 to 2023
$373k
NIAMS NIH HHS P30 AR069655NIAMS NIH HHS P50 AR072000NIAMS NIH HHS R21 AR081050
6 · The paper itself

Abstract

Implant-associated osteomyelitis remains a major orthopaedic problem. As neutrophil swarming to the surgical site is a critical host response to prevent infection, visualization and quantification of this dynamic behavior at the native microenvironment of infection will elucidate previously unrecognized mechanisms central to understanding the host response. We recently developed longitudinal intravital imaging of the bone marrow (LIMB) to visualize fluorescent

Indexed as

bone infectionbone marrowcell motilitycell trackingNeutrophil swarmingTrackMateTrainable Weka Segmentation

Identifiers

PMID38105961
PMCPMC10723476
OpenAlexW4389498282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.