Evidence map›Paper›PMID 38105140›Full record

ArticleVaccine2024

Comparing performance of year-round and campaign-mode influenza vaccination strategies among children aged 6-23 months in Kenya: 2019-2021.

Jeanette Dawa, Rose Jalang'o, Harriet Mirieri, Rosalia Kalani, Doris Marwanga, Kathryn E Lafond, Mary Margaret Muriuki, Joyce Ejoi, Faith Chiguba, Shem Patta and 15 more

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Vaccine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 6 institutions in 2 countries.

Jeanette DawaWashington State University (WSU) Global Health Kenya, Nairobi, Kenya. Electronic address: jdawa@cartafrica.org.
Rose Jalang'oNational Vaccines and Immunisation Program, Ministry of Health, Kenya.
Harriet MirieriWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Rosalia KalaniDivision of Disease Surveillance and Response, Ministry of Health, Kenya.
Doris MarwangaWashington State University (WSU) Global Health Kenya, Nairobi, Kenya.
Kathryn E LafondInfluenza Division, National Center for Immunization and Respiratory Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA.
Mary Margaret MuriukiDepartment of Health, Nakuru County, Kenya.
Joyce EjoiDepartment of Health, Nakuru County, Kenya.
Faith ChigubaDepartment of Health, Mombasa County, Kenya.
Shem PattaDepartment of Health, Mombasa County, Kenya.
Patrick AmothMinistry of Health, Kenya.
Emmanuel OkungaDivision of Disease Surveillance and Response, Ministry of Health, Kenya.
Collins TabuNational Vaccines and Immunisation Program, Ministry of Health, Kenya.
Sandra S ChavesInfluenza Division, National Center for Immunization and Respiratory Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA; Influenza Program, Centers for Disease Control and Prevention, Nairobi, Kenya.
Malembe S EbamaPartnership for Influenza Vaccine Introduction, Task Force for Global Health, Atlanta, GA, USA.
Philip MuthokaMinistry of Health, Kenya.
Virginia NjengaDepartment of Health, Nakuru County, Kenya.
Elizabeth KiptooDepartment of Health, Nakuru County, Kenya.
Isaac JewaDepartment of Health, Mombasa County, Kenya.
Raphael MwanyamawiDepartment of Health, Mombasa County, Kenya.
Joseph BreseePartnership for Influenza Vaccine Introduction, Task Force for Global Health, Atlanta, GA, USA.
M Kariuki NjengaWashington State University (WSU) Global Health Kenya, Nairobi, Kenya; Paul G. Allen School of Global Health, Washington State University (WSU), Pullman, WA, USA.
Eric OsoroWashington State University (WSU) Global Health Kenya, Nairobi, Kenya; Paul G. Allen School of Global Health, Washington State University (WSU), Pullman, WA, USA.
Lucy MeccaNational Vaccines and Immunisation Program, Ministry of Health, Kenya.
Gideon O EmukuleInfluenza Division, National Center for Immunization and Respiratory Diseases, U.S. Centers for Disease Control and Prevention, Atlanta, GA, USA; Influenza Program, Centers for Disease Control and Prevention, Nairobi, Kenya.
Ministry of Health · KEWashington State Department of Health · USNakuru County Council · KECenters for Disease Control and Prevention · USThe Task Force for Global Health · USNational Center for Immunization and Respiratory Diseases · US

Funding

CGH CDC HHS U01 GH002143
6 · The paper itself

Abstract

introductionIn 2016, the Kenya National Immunization Technical Advisory Group requested additional programmatic and cost effectiveness data to inform the choice of strategy for a national influenza vaccination program among children aged 6-23 months of age. In response, we conducted an influenza vaccine demonstration project to compare the performance of a year-round versus campaign-mode vaccination strategy. Findings from this demonstration project will help identify essential learning lessons for a national program.

methodsWe compared two vaccine delivery strategies: (i) a year-round vaccination strategy where influenza vaccines were administered throughout the year at health facilities. This strategy was implemented in Njoro sub-county in Nakuru (November 2019 to October 2021) and Jomvu sub-county in Mombasa (December 2019 to October 2021), (ii) a campaign-mode vaccination strategy where vaccines were available at health facilities over four months. This strategy was implemented in Nakuru North sub-county in Nakuru (June to September 2021) and Likoni sub-county in Mombasa (July to October 2021). We assessed differences in coverage, dropout rates, vaccine wastage, and operational needs.

resultsWe observed similar performance between strategies in coverage of the first dose of influenza vaccine (year-round strategy 59.7 %, campaign strategy 63.2 %). The coverage obtained in the year-round sub-counties was similar (Njoro 57.4 %; Jomvu 63.1 %); however, more marked differences between campaign sub-counties were observed (Nakuru North 73.4 %; Likoni 55.2 %). The campaign-mode strategy exceeded the cold chain capacity of participating health facilities, requiring thrice monthly instead of once monthly deliveries, and was associated with a two-fold increase in workload compared to the year-round strategy (168 vaccines administered per day in the campaign strategy versus 83 vaccines administered per day in the year-round strategy).

conclusionAlthough both strategies had similar coverage levels, the campaign-mode strategy was associated with considerable operational needs that could significantly impact the immunization program.

Indexed as

Immunization ProgramsInfluenza, HumanInfluenza VaccinesVaccinationCost-Benefit AnalysisFemaleHumansInfantKenyaMaleInfluenza VaccinesCoverageInfantsInfluenza vaccinePolicyProgramStrategyTarget population

Identifiers

PMID38105140
PMCPMC11382164
OpenAlexW4389833830

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.