Evidence map›Paper›PMID 38104989›Full record

ArticleInternal medicine (Tokyo, Japan)2024

LMNA::NTRK1 Fusion-positive Leiomyosarcoma: Discrepancy between DNA-based Comprehensive Genomic Profiling and RNA Sequencing.

Norito Suzuki, Masashi Idogawa, Makoto Emori, Kazuyuki Murase, Yohei Arihara, Hajime Nakamura, Makoto Usami, Tomohiro Kubo, Ichiro Kinoshita, Shintaro Sugita and 4 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Norito SuzukiDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Masashi IdogawaDepartment of Medical Genome Sciences, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Japan.
Makoto EmoriDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Japan.
Kazuyuki MuraseDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Yohei AriharaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Hajime NakamuraDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Makoto UsamiDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Tomohiro KuboDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Ichiro KinoshitaDivision of Clinical Cancer Genomics, Hokkaido University Hospital, Japan.
Shintaro SugitaDepartment of Surgical Pathology, Sapporo Medical University School of Medicine, Japan.
Takashi TokinoDepartment of Medical Genome Sciences, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Japan.
Tadashi HasegawaDepartment of Surgical Pathology, Sapporo Medical University School of Medicine, Japan.
Akihiro SakuraiDepartment of Medical Genetics and Genomics, Sapporo Medical University School of Medicine, Japan.
Kohichi TakadaDepartment of Medical Oncology, Sapporo Medical University School of Medicine, Japan.
Sapporo Medical University · JPHokkaido University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 26-year-old man presented with a tumor in the left soleus muscle. The tumor was diagnosed as a locally advanced leiomyosarcoma. The patient was treated with irradiation followed by wide resection. One year after surgery, the patient presented with multiple lung metastases. Despite aggressive sequential chemotherapy, systemic metastatic tumors continued to develop. To explore therapeutic options for the patient, we performed DNA-based CGP with FoundationOne

Indexed as

Lamin Type ALeiomyosarcomaAdultHumansLung NeoplasmsMaleMuscle NeoplasmsOncogene Proteins, FusionReceptor, trkASequence Analysis, RNALamin Type ALMNA protein, humanNTRK1 protein, humanOncogene Proteins, FusionReceptor, trkAleiomyosarcomaNTRK fusion geneRNA sequencing

Identifiers

PMID38104989
PMCPMC11358736
OpenAlexW4389855136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.