Evidence map›Paper›PMID 38104236›Full record

ArticleScientific reports2023

Unveiling the molecular basis of lobeline's allosteric regulation of NMDAR: insights from molecular modeling.

Chandran Remya, E J Variyar, R V Omkumar, C Sadasivan, K V Dileep

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Chandran RemyaLaboratory for Computational and Structural Biology, Jubilee Centre for Medical Research, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, 680005, India.
E J VariyarDepartment of Biotechnology and Microbiology, Kannur University, Dr. Janaki Ammal Campus, Thalassery, Kerala, 670661, India.
R V OmkumarNeurobiology Division, Rajiv Gandhi Centre for Biotechnology, Thycaud PO, Trivandrum, Kerala, 695014, India.
C SadasivanDepartment of Biotechnology and Microbiology, Kannur University, Dr. Janaki Ammal Campus, Thalassery, Kerala, 670661, India.
K V DileepLaboratory for Computational and Structural Biology, Jubilee Centre for Medical Research, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, 680005, India. dileepkvijayan@gmail.com.
Jubilee Mission Medical College and Research Institute · INInter-University Accelerator Centre · INKannur University · INRajiv Gandhi Centre for Biotechnology · IN

Funding

Spices Board India MKT-PD&R/0003/2021-MARKETING
6 · The paper itself

Abstract

Neurological and psychiatric disorders contribute significantly to the global disease burden, adversely affecting the quality of life for both patients and their families. Impaired glutamatergic signaling is considered to be a major cause for most of the neurological and psychiatric disorders. Glutamate receptors are over activated in excitotoxic conditions, leading to dysregulation of Ca

Indexed as

LobelineQuality of LifeAllosteric RegulationHumansModels, MolecularMolecular Docking SimulationReceptors, N-Methyl-D-AspartateLobelineReceptors, N-Methyl-D-Aspartate

Identifiers

PMID38104236
PMCPMC10725453
OpenAlexW4389827993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.