Evidence map›Paper›PMID 38104230›Full record

ArticleScientific reports2023

Hematopoietic and stromal DMP1-Cre labeled cells form a unique niche in the bone marrow.

Sierra H Root, Brya G Matthews, Elena Torreggiani, Hector Leonardo Aguila, Ivo Kalajzic

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. New knock-in mouse linesJBMR plus · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Sierra H RootCenter for Regenerative Medicine and Skeletal Development, MC 3705, School of Dental Medicine, UConn Health, 263 Farmington Ave, Farmington, CT, 06030, USA. sroot@uchc.edu.
Brya G MatthewsCenter for Regenerative Medicine and Skeletal Development, MC 3705, School of Dental Medicine, UConn Health, 263 Farmington Ave, Farmington, CT, 06030, USA.
Elena TorreggianiCenter for Regenerative Medicine and Skeletal Development, MC 3705, School of Dental Medicine, UConn Health, 263 Farmington Ave, Farmington, CT, 06030, USA.
Hector Leonardo AguilaDepartment of Immunology, UConn Health, Farmington, USA.
Ivo KalajzicCenter for Regenerative Medicine and Skeletal Development, MC 3705, School of Dental Medicine, UConn Health, 263 Farmington Ave, Farmington, CT, 06030, USA. ikalaj@uchc.edu.
UConn Health · USUniversity of Auckland · NZ

Funding

Notch Signaling and Bone Fracture HealingR01AR055607 · NIAMS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI Kurt David Hankenson, IVO Kalajzic · 2011 to 2026
$6.3M
Skeletal, Craniofacial and Oral Biology Training GrantT90DE021989 · NIDCR · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI MINA, MINA · 2011 to 2022
$4.5M
NIAMS NIH HHS R01 AR055607NIDCR NIH HHS DE021989NIDCR NIH HHS T90 DE021989
6 · The paper itself

Abstract

Skeletogenesis and hematopoiesis are interdependent. Niches form between cells of both lineages where microenvironmental cues support specific lineage commitment. Because of the complex topography of bone marrow (BM), the identity and function of cells within specialized niches has not been fully elucidated. Dentin Matrix Protein 1 (DMP1)-Cre mice have been utilized in bone studies as mature osteoblasts and osteocytes express DMP1. DMP1 has been identified in CXCL12

Indexed as

Bone MarrowOsteoblastsAnimalsBone Marrow CellsMiceOsteocytesRed Fluorescent ProteinStromal CellsRed Fluorescent ProteintdTomato

Identifiers

PMID38104230
PMCPMC10725438
OpenAlexW4389832395

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.