Evidence map›Paper›PMID 38104191›Full record

ArticleScientific reports2023

Nomogram for predicting severe abdominal pain after initial conventional transarterial chemoembolisation for hepatocellular carcinoma: a retrospective study.

Huixia Qin, Xuhua Xiao, Houxiang Ya, Jinhai Li, Fugang Liang, Haiqing Jin, Lianghuan Liao, Yaohua Li, Jiahui Qin, Jue Yu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Huixia Qin *Department of Interventional Radiology Center, Affiliated Hospital of Guilin Medical University, Guilin, China.
Xuhua Xiao *Department of Gastroenterology, Affiliated Hospital of Guilin Medical University, Guilin, China.
Houxiang Ya *Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Jinhai Li *Department of Liver and Gall Surgery, The Third Affiliated Hospital of Wenzhou Medical University, Zhejiang, China.
Fugang LiangDepartment of Interventional Radiology Center, Affiliated Hospital of Guilin Medical University, Guilin, China.
Haiqing JinDepartment of Interventional Radiology Center, Affiliated Hospital of Guilin Medical University, Guilin, China.
Lianghuan LiaoDepartment of Interventional Radiology Center, Affiliated Hospital of Guilin Medical University, Guilin, China.
Yaohua LiDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Jiahui QinDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Jue YuDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Jing GuDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Chunmei ZhouDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.
Ming JinDepartment of Vascular Intervention, Affiliated Hospital of Guilin Medical University, Guilin, China.
Ying MiaoDepartment of Vascular Intervention, Affiliated Hospital of Guilin Medical University, Guilin, China.
Shuqun LiDepartment of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China. lishuqun2008@126.com.
Guilin Medical University · CNWenzhou Medical University · CN

Funding

Guangxi medical and healthcare appropriate technology development and promotion and application projects S2022132Natural Science Foundation of Guangxi Zhuang Autonomous Region 2022JJA140009Self-financed scientific research projects of Guangxi Autonomous Region Health and Wellness Commission Z-C20230840
6 · The paper itself

Abstract

Transarterial chemoembolisation (TACE) is a standard therapy for hepatocellular carcinoma (HCC). However, adverse events, including abdominal pain, are common. This study aimed to investigate and verify the feasibility of a nomogram model to predict severe abdominal pain after first conventional TACE (cTACE) among patients with HCC. Patients with HCC treated with cTACE between October 28, 2019, and August 5, 2022, at a single centre were enrolled (n = 216). Patients were divided into training and validation cohorts (ratio, 7:3). A visual analogue scale score between 7 and 10 was considered severe abdominal pain. A total of 127 (58.8%) patients complained of severe abdominal pain after first cTACE treatment. The nomogram considered age and tumour number and size. The nomogram demonstrated good discrimination, with a C-index of 0.749 (95% confidence interval [CI], 0.617, 0.881). Further, the C-index in the validation cohort reached 0.728 (95% CI 0.592, 0.864). The calibration curves showed ideal agreement between the prediction and real observations, and the nomogram decision curve analysis performed well. The nomogram model can provide an accurate prediction of severe abdominal pain in patients with HCC after first cTACE, aiding in the personalization of pain management and providing novel insights into hospital nursing.

Indexed as

Carcinoma, HepatocellularChemoembolization, TherapeuticLiver NeoplasmsAbdominal PainHumansNomogramsRetrospective Studies

Identifiers

PMID38104191
PMCPMC10725474
OpenAlexW4389828734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.