Evidence map›Paper›PMID 38104084›Full record

ArticleBMC emergency medicine2023

Gender disparities in the mediating role of symptom knowledge level in reducing acute coronary syndrome (ACS) decision delay: Findings from a community-based study in China.

Siyue Wang, Junxian Song, Chongyou Lee, Jin Jiang, Mengying Wang, Dongjing Liu, Zhuqing Wang, Yuan Yuan, Wenyong Li, Ren Zhou and 6 more

Abstract read
In one paragraph

Article in BMC emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

16 authors.

Siyue WangPeking University Health Science Center, Beijing, China.
Junxian SongCenter for Cardiovascular Translational Research, Peking University People's Hospital Beijing, Beijing, China.
Chongyou LeeCenter for Cardiovascular Translational Research, Peking University People's Hospital Beijing, Beijing, China.
Jin JiangPeking University Health Science Center, Beijing, China.
Mengying WangPeking University Health Science Center, Beijing, China.
Dongjing LiuPeking University Health Science Center, Beijing, China.
Zhuqing WangPeking University Health Science Center, Beijing, China.
Yuan YuanPeking University Health Science Center, Beijing, China.
Wenyong LiPeking University Health Science Center, Beijing, China.
Ren ZhouPeking University Health Science Center, Beijing, China.
Hongchen ZhengPeking University Health Science Center, Beijing, China.
Jianmin WeiBeijing Red Cross Emergency Rescue Center, Beijing, China.
Yonghua HuPeking University Health Science Center, Beijing, China. yhhu@bjmu.edu.cn.
Tao WuPeking University Health Science Center, Beijing, China. twu@bjmu.edu.cn.
Zhenbiao TianBeijing Red Cross Emergency Rescue Center, Beijing, China.
Hong ChenCenter for Cardiovascular Translational Research, Peking University People's Hospital Beijing, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImplementing training programs to educate patients on the prodromal symptoms of acute coronary syndrome (ACS) may assist patients in accurately recognizing these symptoms, and ultimately decrease their time delay in seeking emergency medical services (EMS). However, the effectiveness of this approach remains uncertain, particularly among the Chinese population.

methodsA cross-sectional study was conducted within 22 communities in Beijing, China between 2015 and 2018, with a total of 1099 participants recruited. The study utilized a standardized questionnaire to evaluate the presence of intentional decision delay in turning to EMS under a hypothetical chest pain, the participants' knowledge of ACS prodromal symptoms, and whether they had ever received any training programs aimed at increasing their symptom knowledge. Mediation analysis was performed with regression models and bootstrapping methods, and gender difference was further analyzed through moderated mediation analysis.

resultsA total of 1099 participants (58.2% female, median [IQR] age 34 [20]) were included in the study. The results of the mediation analysis indicated that training programs were associated with a decrease risk in decision delay, with increased knowledge playing a mediating role (mediation effect/total effect = 36.59%, P < 0.0001). Gender modified this mediation effect, with it being observed only in the male group. Specifically, training programs were not found to significantly decrease decision delay among females (P > 0.05), even though they did improve women's knowledge of ACS prodromal symptoms (β = 0.57, P = 0.012).

conclusionThe results suggested a relationship between prior training programs and reduced decision delay, with increased knowledge of prodromal symptoms of ACS serving as a mediator. However, the effect was only observed in male participants and not in female participants. This highlights the notion that mere transfer of knowledge regarding ACS prodromal symptoms may not be sufficient to mitigate decision delay in the female population. Further research is needed to corroborate these results and to gain deeper insights into the gender-specific barriers encountered in this study.

Indexed as

Acute Coronary SyndromeEmergency Medical ServicesAdultChinaCross-Sectional StudiesFemaleHumansMaleProdromal SymptomsAcute coronary syndromeDecision delayKnowledge of prodromal symptomsPre-hospital delay

Identifiers

PMID38104084
PMCPMC10725594

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.