Evidence map›Paper›PMID 38103769›Full record

SynthesisThe American journal of cardiology2024

Meta-Analysis of the Performance of AI-Driven ECG Interpretation in the Diagnosis of Valvular Heart Diseases.

Sahib Singh, Rahul Chaudhary, Kevin P Bliden, Udaya S Tantry, Paul A Gurbel, Shyam Visweswaran, Matthew E Harinstein

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in The American journal of cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
  6. New perspectives in the management of adults with congenital heart disease: insights from the 2025 ACHD Congress.European heart journal supplements : journal of the European Society of Cardiology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Artificial intelligence for cardiology: from diagnosis to management.Therapeutic advances in cardiovascular disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sahib SinghDepartment of Medicine, Sinai Hospital of Baltimore, Baltimore, Maryland.
Rahul ChaudharyArtificial Intelligence for Holistic Evaluation and Advancement of Cardiovascular Thrombosis (AI-HEART) Lab, Pittsburgh, Pennsylvania; Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Intelligent Systems Program, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address: chaudhar@pitt.edu.
Kevin P BlidenDepartment of Cardiology, Sinai Center of Thrombosis Research and Drug Development, Baltimore, Maryland.
Udaya S TantryDepartment of Cardiology, Sinai Center of Thrombosis Research and Drug Development, Baltimore, Maryland.
Paul A GurbelDepartment of Medicine, Sinai Hospital of Baltimore, Baltimore, Maryland; Department of Cardiology, Sinai Center of Thrombosis Research and Drug Development, Baltimore, Maryland.
Shyam VisweswaranIntelligent Systems Program, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, Pennsylvania.
Matthew E HarinsteinHeart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Funding

Training Program in Imaging Sciences in Translational Cardiovascular ResearchT32HL129964 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Flordeliza S Villanueva · 2016 to 2026
$4.7M
NHLBI NIH HHS T32 HL129964
6 · The paper itself

Abstract

Valvular heart diseases (VHDs) significantly impact morbidity and mortality rates worldwide. Early diagnosis improves patient outcomes. Artificial intelligence (AI) applied to electrocardiogram (ECG) interpretation presents a promising approach for early VHD detection. We conducted a meta-analysis on the efficacy of AI models in this context. We reviewed databases including PubMed, MEDLINE, Embase, Scopus, and Cochrane until August 20, 2023, focusing on AI for ECG-based VHD detection. The outcomes included pooled accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value. The pooled proportions were derived using a random-effects model with 95% confidence intervals (CIs). Study heterogeneity was evaluated with the I-squared statistic. Our analysis included 10 studies, involving ECG data from 713,537 patients. The AI algorithms mainly screened for aortic stenosis (n = 6), mitral regurgitation (n = 4), aortic regurgitation (n = 3), mitral stenosis (n = 1), mitral valve prolapse (n = 2), and tricuspid regurgitation (n = 1). A total of 9 studies used convolution neural network models, whereas 1 study combined the strengths of support vector machine logistic regression and multilayer perceptron for ECG interpretation. The collective AI models demonstrated a pooled accuracy of 81% (95% CI 73 to 89, I

Indexed as

Aortic Valve StenosisHeart Valve DiseasesMitral Valve InsufficiencyArtificial IntelligenceElectrocardiographyHumansaortic stenosisartificial intelligenceelectrocardiogramsmitral regurgitationvalvular heart disease

Identifiers

PMID38103769
PMCPMC10842912

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.