Evidence map›Paper›PMID 38103071›Full record

ReviewArchives of toxicology2024

Molecular mechanisms of artificial light at night affecting circadian rhythm disturbance.

Ting Lei, Hui Hua, Huiying Du, Jie Xia, Dandan Xu, Wei Liu, Yutong Wang, Tianyao Yang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  8. Influence of Artificial Light at Night on Thyroid Gland Histology inAnimals : an open access journal from MDPI · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ting Lei *Key Laboratory of Environmental Stress and Chronic Disease Control and Prevention (China Medical University), Ministry of Education, Shenyang, 110122, Liaoning, China.
Hui Hua *Department of Nutrition, School of Public Health, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China.
Huiying DuKey Laboratory of Environmental Stress and Chronic Disease Control and Prevention (China Medical University), Ministry of Education, Shenyang, 110122, Liaoning, China.
Jie XiaKey Laboratory of Environmental Stress and Chronic Disease Control and Prevention (China Medical University), Ministry of Education, Shenyang, 110122, Liaoning, China.
Dandan XuKey Laboratory of Environmental Stress and Chronic Disease Control and Prevention (China Medical University), Ministry of Education, Shenyang, 110122, Liaoning, China.
Wei LiuKey Laboratory of Environmental Stress and Chronic Disease Control and Prevention (China Medical University), Ministry of Education, Shenyang, 110122, Liaoning, China.
Yutong WangDepartment of Oncology, Shengjing Hospital of China Medical University, Shenyang, 110004, Liaoning, China. 13149837297@163.com.
Tianyao YangKey Laboratory of Environmental Stress and Chronic Disease Control and Prevention (China Medical University), Ministry of Education, Shenyang, 110122, Liaoning, China. tyyang@cmu.edu.cn.ORCID 0000-0003-0613-1338
China Medical University · CNShenyang Center for Disease Control and Prevention · CNXuzhou Medical College · CN

Funding

National Natural Science Foundation of China NSFC 82204000Shanghai Sailing Program 21YF1451500
6 · The paper itself

Abstract

Artificial light at night (ALAN) pollution has been regarded as a global environmental concern. More than 80% of the global population is exposed to light pollution. Exacerbating this issue, artificially lit outdoor areas are growing by 2.2% per year, while continuously lit areas have brightened by 2.2% each year due to rapid population growth and expanding urbanization. Furthermore, the increasing prevalence of night shift work and smart device usage contributes to the inescapable influence of ALAN. Studies have shown that ALAN can disrupt endogenous biological clocks, resulting in a disturbance of the circadian rhythm, which ultimately affects various physiological functions. Up until now, scholars have studied various disease mechanisms caused by ALAN that may be related to the response of the circadian system to light. This review outlines the molecular mechanisms by which ALAN causes circadian rhythm abnormalities in sleep disorders, endocrine diseases, cardiovascular disease, cancer, immune impairment, depression, anxiety and cognitive impairments.

Indexed as

Light PollutionShift Work ScheduleCircadian RhythmEnvironmental PollutionLightingALANCentral clockCircadian rhythmClock genesPeripheral clocks

Identifiers

PMID38103071
OpenAlexW4389833238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.