Evidence map›Paper›PMID 38102699›Full record

Observational studyEuropean journal of medical research2023

Improved oxygenation in prone positioning of mechanically ventilated patients with COVID-19 acute respiratory distress syndrome is associated with decreased pulmonary shunt fraction: a prospective multicenter study.

Piotr Harbut, Francesca Campoccia Jalde, Martin Dahlberg, Anders Forsgren, Elisabeth Andersson, Andreas Lundholm, Jaroslaw Janc, Patrycja Lesnik, Michal Suchanski, Pawel Zatorski and 3 more

Open access · goldAbstract readObservational StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European journal of medical research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Prone positioning.Intensive care medicine · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Piotr HarbutDepartment of Clinical Sciences Danderyd, Karolinska Institutet, Stockholm, Sweden.
Francesca Campoccia JaldeDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.
Martin DahlbergDepartment of Clinical Science and Education Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.
Anders ForsgrenDepartment of Clinical Science and Education Södersjukhuset, Section for Anesthesiology and Intensive Care, Karolinska Institutet, Sjukhusbacken 10, SE-118 83, Stockholm, Sweden.
Elisabeth AnderssonDepartment of Clinical Science and Education Södersjukhuset, Section for Anesthesiology and Intensive Care, Karolinska Institutet, Sjukhusbacken 10, SE-118 83, Stockholm, Sweden.
Andreas LundholmDepartment of Clinical Sciences Danderyd, Karolinska Institutet, Stockholm, Sweden.
Jaroslaw Janc4th Military Clinical Hospital, Wroclaw, Poland.
Patrycja Lesnik4th Military Clinical Hospital, Wroclaw, Poland.
Michal Suchanski4th Military Clinical Hospital, Wroclaw, Poland.
Pawel ZatorskiMedical University of Warsaw, Warsaw, Poland.
Janusz TrzebickiMedical University of Warsaw, Warsaw, Poland.
Tomasz SkalecWroclaw Medical University, Wroclaw, Poland.
Mattias GüntherDepartment of Clinical Science and Education Södersjukhuset, Section for Anesthesiology and Intensive Care, Karolinska Institutet, Sjukhusbacken 10, SE-118 83, Stockholm, Sweden. mattias.gunther@ki.se.
Karolinska Institutet · SEStockholm South General Hospital · SEMedical University of Warsaw · PLKarolinska University Hospital · SEWroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProne position is used in acute respiratory distress syndrome and in coronavirus disease 2019 (Covid-19) acute respiratory distress syndrome (ARDS). However, physiological mechanisms remain unclear. The aim of this study was to determine whether improved oxygenation was related to pulmonary shunt fraction (Q's/Q't), alveolar dead space (Vd/Vtalv) and ventilation/perfusion mismatch (V'

methodsThis was an international, prospective, observational, multicenter, cohort study, including six intensive care units in Sweden and Poland and 71 mechanically ventilated adult patients.

resultsProne position increased PaO

conclusionsImproved oxygenation by prone positioning in COVID-19 ARDS patients was primarily associated with a decrease in pulmonary shunt fraction. Dead space remained high and the global V'

Indexed as

COVID-19Respiratory Distress SyndromeAdultCohort StudiesHemodynamicsHumansProne PositionProspective StudiesPulmonary Gas ExchangeRespiration, ArtificialAcute respiratory distress syndromeCOVID-19Intensive careProne positionPulmonary shunt fraction

Identifiers

PMID38102699
PMCPMC10725003
OpenAlexW4389804574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.