Trial reportBMC medical informatics and decision making2023
The effect of health literacy intervention on adherence to medication of uncontrolled hypertensive patients using the M-health.
Trial report in BMC medical informatics and decision making, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Health literacy training for older adults: a systematic review with meta-analysis.BMC geriatrics · 2026Pooled it
- Association of Health Literacy with Sociodemographic Factors and Medication Adherence Among Primary Health Care Users in Montenegro.Healthcare (Basel, Switzerland) · 2026Article
- Access to cervical cancer care in sub-Saharan Africa: a narrative review of barriers and opportunities.Frontiers in public health · 2026Review
- Perceptions, Practices and mHealth Readiness for Blood Pressure Self-Monitoring Among Ghanaian Hypertensive Patients.International journal of hypertension · 2026Article
- Effects of a transformative learning theory-based health literacy enhancement program on self-management behaviors and blood pressure in adults with uncontrolled hypertension in Thailand: A cluster randomized controlled trial.Belitung nursing journal · 2026Article
- Medication Adherence Among Hypertensive Patients in Bangladesh: A Nationwide Analysis of Gender and Urban-Rural Disparities.International journal of hypertension · 2026Article
- Article
- Improving Therapeutic Adherence and Reducing Therapeutic Inertia in the Management of People with Cardiometabolic Diseases: A Call-to-Action from the Middle East.Advances in therapy · 2025Review
- Adherence to pharmacological therapy for hypertension in Portugal: a health professionals focus groups study.BMC primary care · 2025Article
- Health Literacy and Treatment Adherence in Older Patients with Hypertension.Research in heart yield and translational medicine · 2025Article
- An intervention study on the secondary prevention medication adherence of ischemic stroke patients based on the protection motivation theory combined with medication literacy education in the AI-HEALS: a randomized controlled trial protocol.Frontiers in public health · 2025Article
- Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven that patients' medication adherence is regarded as the major part of disease control and improving health literacy can be effective in promoting adherence to healthy behaviors, the present study aimed to investigate the effect of health literacy intervention based on the medication adherence among uncontrolled hypertensive patients using mobile health (M-health).
methodsAn interventional study with a quasi-experimental design, was conducted on 118 uncontrolled hypertensive patients. Participants were randomly divided into the intervention (n = 59) and control (n = 59) groups using blocked randomization. In the intervention group, a mobile health (M-health) program was designed using programmed instruction to improve patients' health literacy over a period of 3 months. Data was collected by administering health literacy and medication adherence questionnaires to participants before and after the intervention. The analysis involved using the independent sample t-test to compare the variables before and after the study.
resultsBefore the intervention, the total score of health literacy was 33.34 and 33.14 in the intervention and control groups, respectively. After the intervention, it increased to 40.36 and 34.20 in the intervention and control groups, respectively, which was statistically significant in the intervention group (p = 0.01). Moreover, the medication adherence score of the intervention group significantly increased after the intervention. Both systolic and diastolic blood pressure decreased in the intervention group. However, it should be noted that the decrease in systolic blood pressure by 148.98 was statistically significant, while the decrease observed in diastolic blood pressure in the intervention group was not statistically significant (p = 0.08).
conclusionThe application of programmed instruction through M-Health has shown a positive effect on the health literacy of uncontrolled hypertensive patients. In addition to detecting and treating patients, it is important to prioritize the improvement of health literacy in terms of medication adherence and the adoption of healthy behaviors.
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