Evidence map›Paper›PMID 38102597›Full record

SynthesisBiomedical engineering online2023

Artificial intelligence in glaucoma: opportunities, challenges, and future directions.

Xiaoqin Huang, Md Rafiqul Islam, Shanjita Akter, Fuad Ahmed, Ehsan Kazami, Hashem Abu Serhan, Alaa Abd-Alrazaq, Siamak Yousefi

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Biomedical engineering online, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Advances in OCT Angiography.Translational vision science & technology · 2025
    Review
  11. Review
  12. Artificial Intelligence for Optical Coherence Tomography in Glaucoma.Translational vision science & technology · 2025
    Review
  13. Artificial intelligence in ophthalmology: opportunities, challenges, and ethical considerations.Medical hypothesis, discovery & innovation ophthalmology journal · 2025
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 6 countries.

Xiaoqin Huang *Department of Ophthalmology, University of Tennessee Health Science Center, Memphis, USA.
Md Rafiqul Islam *Business Information Systems, Australian Institute of Higher Education, Sydney, Australia.
Shanjita AkterSchool of Computer Science, Taylors University, Subang Jaya, Malaysia.
Fuad AhmedDepartment of Computer Science & Engineering, Islamic University of Technology (IUT), Gazipur, Bangladesh.
Ehsan KazamiOphthalmology, General Hospital of Mahabad, Urmia University of Medical Sciences, Urmia, Iran.
Hashem Abu SerhanDepartment of Ophthalmology, Hamad Medical Corporations, Doha, Qatar.
Alaa Abd-AlrazaqAI Center for Precision Health, Weill Cornell Medicine-Qatar, Doha, Qatar.
Siamak YousefiDepartment of Ophthalmology, University of Tennessee Health Science Center, Memphis, USA. siamak.yousefi@uthsc.edu.
University of Tennessee Health Science Center · USAustralian Institute of Business · AUHamad Medical Corporation · QAIslamic University of Technology · BDTaylor's University · MYUrmia University · IRWeill Cornell Medical College in Qatar · QA

Funding

Predicting the risk of glaucoma from structural, functional, and genetic factors using artificial intelligenceR01EY033005 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI YOUSEFI, SIAMAK · 2022 to 2025
$2.4M
Improved Glaucoma Monitoring Using Artificial-Intelligence Enabled DashboardR21EY031725 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI YOUSEFI, SIAMAK · 2020 to 2022
$545k
NEI NIH HHS EY031725NEI NIH HHS EY033005NEI NIH HHS R01 EY033005NEI NIH HHS R21 EY031725
6 · The paper itself

Abstract

Artificial intelligence (AI) has shown excellent diagnostic performance in detecting various complex problems related to many areas of healthcare including ophthalmology. AI diagnostic systems developed from fundus images have become state-of-the-art tools in diagnosing retinal conditions and glaucoma as well as other ocular diseases. However, designing and implementing AI models using large imaging data is challenging. In this study, we review different machine learning (ML) and deep learning (DL) techniques applied to multiple modalities of retinal data, such as fundus images and visual fields for glaucoma detection, progression assessment, staging and so on. We summarize findings and provide several taxonomies to help the reader understand the evolution of conventional and emerging AI models in glaucoma. We discuss opportunities and challenges facing AI application in glaucoma and highlight some key themes from the existing literature that may help to explore future studies. Our goal in this systematic review is to help readers and researchers to understand critical aspects of AI related to glaucoma as well as determine the necessary steps and requirements for the successful development of AI models in glaucoma.

Indexed as

Deep LearningGlaucomaOphthalmologyArtificial IntelligenceHumansMachine LearningArtificial intelligenceDeep learningGlaucomaMachine learning

Identifiers

PMID38102597
PMCPMC10725017
OpenAlexW4389804656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.