Evidence map›Paper›PMID 38102481›Full record

ArticleMolecular psychiatry2024

Intranasal oxytocin in a genetic animal model of autism.

Jakub Szabó, Matúš Mlynár, Andrej Feješ, Emese Renczés, Veronika Borbélyová, Daniela Ostatníková, Peter Celec

Open access · hybridAbstract read
In one paragraph

Article in Molecular psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Lasting effects of early-life oxytocin treatment on LTP and episodic memory in a mouse model of Fragile X syndrome.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. How does oxytocin modulate human behavior?Molecular psychiatry · 2025
    Review
  7. Article
  8. Article
  9. Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jakub SzabóInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.ORCID 0000-0002-6085-1291
Matúš MlynárInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.ORCID 0009-0000-5504-675X
Andrej FeješInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Emese RenczésInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Veronika BorbélyováInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Daniela OstatníkováInstitute of Physiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.
Peter CelecInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia. peter.celec@uniba.sk.ORCID 0000-0001-5883-3580
Comenius University Bratislava · SK

Funding

Agentúra na Podporu Výskumu a Vývoja (Slovak Research and Development Agency) APVV-20-0185
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders mainly characterized by deficient sociability and repetitive behaviors. Effective treatment for the core symptoms of ASD is still lacking. Behavioral interventions show limited effectiveness, while pharmacotherapy focuses on the amelioration of secondary symptomatology. Oxytocin (OXT) is a neuropeptide known for its prosocial impact, making it a candidate drug for ASD treatment. Its alleviating effect has been and still is widely researched, but outcomes reported by clinical studies are ambiguous. We examined the effect of daily intranasal OXT (0.8 IU/kg) administration for 4 weeks on the ASD-like phenotype in Shank3

Indexed as

Administration, IntranasalAutism Spectrum DisorderDisease Models, AnimalMice, KnockoutOxytocinSocial BehaviorAnimalsAutistic DisorderBehavior, AnimalExploratory BehaviorMaleMiceMice, Inbred C57BLMicrofilament ProteinsNerve Tissue ProteinsMicrofilament ProteinsNerve Tissue ProteinsOxytocinShank3 protein, mouse

Identifiers

PMID38102481
PMCPMC11116098
OpenAlexW4389788886

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.