Evidence map›Paper›PMID 38102385›Full record

ReviewNature reviews. Urology2024

Mechanical characteristics of the ureter and clinical implications.

Sorcha O'Meara, Eoghan M Cunnane, Stefanie M Croghan, Connor V Cunnane, Michael T Walsh, Fergal J O'Brien, Niall F Davis

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sorcha O'MearaDepartment of Surgery, Royal College of Surgeons of Ireland (RCSI), Dublin, Ireland. sorchaomeara@rcsi.ie.ORCID 0000-0003-2502-5450
Eoghan M CunnaneBiomaterials Cluster, Bernal Institute, University of Limerick, Limerick, Ireland.ORCID 0000-0001-5599-9040
Stefanie M CroghanDepartment of Surgery, Royal College of Surgeons of Ireland (RCSI), Dublin, Ireland.
Connor V CunnaneBiomaterials Cluster, Bernal Institute, University of Limerick, Limerick, Ireland.
Michael T WalshBiomaterials Cluster, Bernal Institute, University of Limerick, Limerick, Ireland.
Fergal J O'BrienTissue Engineering Research Group, Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.ORCID 0000-0003-2030-8005
Niall F DavisDepartment of Surgery, Royal College of Surgeons of Ireland (RCSI), Dublin, Ireland.
Royal College of Surgeons in Ireland · IEUniversity of Limerick · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ureteric wall is a complex multi-layered structure. The ureter shows variation in passive mechanical properties, histological morphology and insertion forces along the anatomical length. Ureter mechanical properties also vary depending on the direction of tensile testing and the anatomical region tested. Compliance is greatest in the proximal ureter and lower in the distal ureter, which contributes to the role of the ureter as a high-resistance sphincter. Similar to other human tissues, the ureteric wall remodels with age, resulting in changes to the mechanical properties. The passive mechanical properties of the ureter vary between species, and variation in tissue storage and testing methods limits comparison across some studies. Knowledge of the morphological and mechanical properties of the ureteric wall can aid in understanding urine transport and safety thresholds in surgical techniques. Indeed, various factors alter the forces required to insert access sheaths or scopes into the ureter, including sheath diameter, safety wires and medications. Future studies on human ureteric tissue both in vivo and ex vivo are required to understand the mechanical properties of the ureter and how forces influence these properties. Testing of instrument insertion forces in humans with a focus on defining safe upper limits and techniques to reduce trauma are also needed. Last, evaluation of dilatation limits in the mid and proximal ureter and clarification of tensile strength anisotropy in human specimens are necessary.

Indexed as

UreterHumans

Identifiers

PMID38102385
OpenAlexW4389794263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.