Evidence map›Paper›PMID 38102125›Full record

ArticleCell death & disease2023

New ruthenium-xanthoxylin complex eliminates colorectal cancer stem cells by targeting the heat shock protein 90 chaperone.

Luciano de S Santos, Valdenizia R Silva, Maria V L de Castro, Rosane B Dias, Ludmila de F Valverde, Clarissa A G Rocha, Milena B P Soares, Claudio A Quadros, Edjane R Dos Santos, Regina M M Oliveira and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Cancer Stem Cells from Definition to Detection and Targeted Drugs.International journal of molecular sciences · 2024
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 1 country.

Luciano de S SantosGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, 40296-710, Brazil.
Valdenizia R SilvaGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, 40296-710, Brazil.
Maria V L de CastroGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, 40296-710, Brazil.
Rosane B DiasGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, 40296-710, Brazil.
Ludmila de F ValverdeGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, 40296-710, Brazil.
Clarissa A G RochaGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, 40296-710, Brazil.
Milena B P SoaresGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, 40296-710, Brazil.
Claudio A QuadrosSão Rafael Hospital, Rede D'Or/São Luiz, Salvador, BA, 41253-190, Brazil.
Edjane R Dos SantosInstitute of Natural, Human and Social Sciences, Federal University of Mato Grosso, Sinop, MT, 78557-267, Brazil.
Regina M M OliveiraCoordination of Science and Technology, Balsas Science Center, Federal University of Maranhão, Balsas, MA, 65800-000, Brazil.
Rose M CarlosDepartment of Chemistry, Federal University of São Carlos, São Carlos, SP, 13561-901, Brazil.
Paulo C L NogueiraDepartment of Chemistry, Federal University of Sergipe, São Cristóvão, SE, 49100-000, Brazil.
Daniel P BezerraGonçalo Moniz Institute, Oswaldo Cruz Foundation (IGM-FIOCRUZ/BA), Salvador, BA, 40296-710, Brazil. daniel.bezerra@fiocruz.br.ORCID 0000-0002-6774-2063
Fundação Oswaldo Cruz · BRUniversidade Federal da Bahia · BRServiço Nacional de Aprendizagem Industrial · BRUniversidade do Estado da Bahia · BRUniversidade Federal de Mato Grosso · BRUniversidade Federal de São Carlos · BRUniversidade Federal de Sergipe · BRUniversidade Federal do Maranhão · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brazilian Federal Agency for the Support and Evaluation of Graduate Education) 001
6 · The paper itself

Abstract

In this work, we describe a novel ruthenium-xanthoxylin complex, [Ru(phen)

Indexed as

Colorectal NeoplasmsRutheniumAcetophenonesAnimalsCell Line, TumorCell ProliferationGlycogen Synthase Kinase 3 betaHCT116 CellsHSP90 Heat-Shock ProteinsHumansMiceSignal TransductionAcetophenonesGlycogen Synthase Kinase 3 betaHSP90 Heat-Shock ProteinsRutheniumxanthoxyline

Identifiers

PMID38102125
PMCPMC10724293
OpenAlexW4389790558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.