Evidence map›Paper›PMID 38101620›Full record

ArticleJournal of lipid research2024

Effects of apolipoprotein H downregulation on lipid metabolism, fatty liver disease, and gut microbiota dysbiosis.

Yaming Liu, Yiqun Zhao, Qiusong Liu, Binbin Li, P Vineeth Daniel, Binbin Chen, Zeyi Wu

Open access · goldAbstract read
In one paragraph

Article in Journal of lipid research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. BLOC1S1 Attenuates B. Melitensis 16M LPS-Triggered Autophagy by Spatial Confinement of TDP-43.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  4. Patterns of lipid profile and genetic variations in South Asians.Cardiovascular diabetology. Endocrinology reports · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Updated mechanisms of MASLD pathogenesis.Lipids in health and disease · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Yaming LiuDepartment of Gastroenterology and Hepatology, Xiamen University Zhongshan Hospital, Xiamen, FJ, China; Department of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, FJ, China. Electronic address: yaming0856@gmail.com.
Yiqun ZhaoDepartment of Gastroenterology and Hepatology, Xiamen University Zhongshan Hospital, Xiamen, FJ, China; Department of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, FJ, China.
Qiusong LiuDepartment of Tumor and Vascular Interventional Radiology, Xiamen University Zhongshan Hospital, Xiamen, FJ, China.
Binbin LiDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
P Vineeth DanielDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Binbin ChenDepartment of Digestive Diseases, School of Medicine, Xiamen University, Xiamen, FJ, China.
Zeyi WuDepartment of Computer Science and Engineering, University of California, San Diego, CA, USA.
Xiamen University · CNMayo Clinic in Arizona · USUniversity of California San Diego · USZhongshan Hospital of Xiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apolipoprotein H (APOH) downregulation can cause hepatic steatosis and gut microbiota dysbiosis. However, the mechanism by which APOH-regulated lipid metabolism contributes to metabolic dysfunction-associated steatotic liver disease (MASLD) remains undetermined. Herein, we aim to explore the regulatory effect of APOH, mediated through various pathways, on metabolic homeostasis and MASLD pathogenesis. We analyzed serum marker levels, liver histopathology, and cholesterol metabolism-related gene expression in global ApoH

Indexed as

Gastrointestinal MicrobiomeNon-alcoholic Fatty Liver DiseaseAnimalsbeta 2-Glycoprotein IDown-RegulationDysbiosisFatty AcidsHumansLipid MetabolismLiverMaleMiceMice, Inbred C57BLbeta 2-Glycoprotein IFatty Acidsapolipoprotein Hbile acids and saltscholesterol/metabolismde novo lipogenesisgut microbiotahepatocytetriglycerides

Identifiers

PMID38101620
PMCPMC10818206
OpenAlexW4389737122

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.