Evidence map›Paper›PMID 38100725›Full record

ArticleChronic respiratory disease

Association between non-cystic fibrosis bronchiectasis and the risk of incident dementia: A nationwide cohort study.

Sang Hyuk Kim, Kyungdo Han, Jongkyu Park, Dong Won Park, Ji-Yong Moon, Yun Su Sim, Tae-Hyung Kim, Sang-Heon Kim, Jang Won Sohn, Ho Joo Yoon and 2 more

Open access · goldAbstract read
In one paragraph

Article in Chronic respiratory disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 17 citations in OpenAlex.

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  13. COVID-19 and Long-term Risk of Ischemic Heart Disease in Asthma.Allergy, asthma & immunology research · 2025
    Article
  14. Secondary Immunodeficiency and Non-cystic Fibrosis Bronchiectasis.Tuberculosis and respiratory diseases · 2024
    Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Sang Hyuk KimDepartment of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.ORCID 0000-0002-0410-8524
Kyungdo HanDepartment of Statistics and Actuarial Science, Soongsil University, Seoul, Korea.
Jongkyu ParkDepartment of Neurology, Soonchunhyang University College of Medicine, Soonchunhyang University, Cheonan, Korea.
Dong Won ParkDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Ji-Yong MoonDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.ORCID 0000-0003-2459-3448
Yun Su SimDepartment of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.ORCID 0000-0002-3746-4947
Tae-Hyung KimDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Sang-Heon KimDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Jang Won SohnDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Ho Joo YoonDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Hyun LeeDepartment of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
Hayoung ChoiDepartment of Internal Medicine, Hallym University College of Medicine, Seoul, Korea.ORCID 0000-0003-4812-0653
Hanyang University · KRHallym University · KRSoonchunhyang University · KRSoongsil University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic lung diseases, such as chronic obstructive pulmonary disease or asthma, are associated with an increased risk of dementia. However, few data are available regarding the risk of dementia in individuals with bronchiectasis.

objectivesTo explore the association between bronchiectasis and the risk of incident dementia using a longitudinal population-based cohort.

methodsA total of 4,068,560 adults older than 50 years without previous dementia were enrolled from the Korean National Health Insurance Service database in 2009. They were followed up until the date of the diagnosis of dementia or December 31, 2020. The study exposure was the diagnosis of bronchiectasis, and the primary outcome was incident dementia comprising Alzheimer's disease and vascular dementia.

resultsDuring the median follow-up duration of 9.3 years, the incidence of all-cause dementia was 1.6-fold higher in individuals with bronchiectasis than in those without bronchiectasis (15.0 vs. 9.3/1000 person-years,

conclusionBronchiectasis was associated with an increased risk of dementia, especially Alzheimer's disease.

Indexed as

Alzheimer DiseaseBronchiectasisDementia, VascularAdultCohort StudiesFibrosisHumansRisk FactorsAlzheimer diseaseBronchiectasisdementiaepidemiologyvascular dementia

Identifiers

PMID38100725
PMCPMC10725102
OpenAlexW4389799594

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.