ArticleScience immunology2023
Acquisition of suppressive function by conventional T cells limits antitumor immunity upon T
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Science immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 30 citations in OpenAlex.
- Neoadjuvant Fc-enhanced anti-CTLA-4 targets Tregs to augment androgen deprivation in high-risk prostate cancer: A randomized phase I trial.Cell reports. Medicine · 2026Trial
- Mechanistic reprogramming of the mtDNA-cGAS-STING axis in cellular senescence: from mitochondrial homeostatic disruption to inflammatory and immune outcomes.Biogerontology · 2026Review
- Molecular heterogeneity and clonal origin of CCR8Nature communications · 2026Article
- Review
- Mapping the research landscape of the correlation between radiotherapy and tumor immune microenvironment: A bibliometric analysis.Precision radiation oncology · 2026Article
- Cell membranes-encapsulated gadolinium-doped carbon dots for the efficient photothermal and immunotherapeutic synergistic treatment of hepatocellular carcinoma.Journal of nanobiotechnology · 2026Article
- Regulatory T Cells Along the Pancreatitis-Pancreatic Cancer Continuum: Context-Dependent Immune Control and Therapeutic Opportunities.International journal of general medicine · 2026Review
- Stem-like CD4 T cells in tumors: an emerging framework for antitumor immunity.Frontiers in immunology · 2026Review
- Risk factors and immune landscape of early local tumor progression after microwave ablation for lung cancer: a retrospective nested case-control study.Frontiers in immunology · 2026Article
- Regulatory T cells in the tumour microenvironment.Nature reviews. Cancer · 2025Review
- Immunometabolism of regulatory T cells in cancer.Oncogene · 2025Review
- Frontiers and Controversies in De Novo Gastrointestinal Tumors After Organ Transplantation: Current Progress and Future Directions.Annals of surgical oncology · 2025Review
- Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment.Journal for immunotherapy of cancer · 2025Article
- Immunocytes in the tumor microenvironment: recent updates and interconnections.Frontiers in immunology · 2025Review
- Interaction between nasal epithelial cells and Tregs in allergic rhinitis responses to allergen via CCL1/CCR8.Frontiers in immunology · 2025Article
- Recent advances in novel tumor immunotherapy strategies based on regulating the tumor microenvironment and immune checkpoints.Frontiers in immunology · 2025Review
- Metabolic targeting of regulatory T cells in oral squamous cell carcinoma: new horizons in immunotherapy.Molecular cancer · 2024Review
- Epigenetics behind CD8Genes and immunity · 2024Review
- Depletion of conventional CD4Journal for immunotherapy of cancer · 2024Article
- Review
Corrections and comments
- Erratum issued
Authors and funding
23 authors at 7 institutions in 4 countries.
Sarah K WhitesideDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0003-4354-4713
Francis M GrantImmunology Programme, Babraham Institute, Babraham Research Campus, Cambridge, Cambridgeshire CB22 3AT, UK.ORCID 0000-0001-6885-481X
Giorgia AlvisiLaboratory of Translational Immunology, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy.
James ClarkeLa Jolla Institute for Allergy and Immunology, La Jolla, CA, USA.
Leqi TangDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0002-3961-2130
Charlotte J ImianowskiDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0002-7116-7591
Baojie ZhangDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.
Alexander C EvansDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0002-6363-2684
Alexander J WesolowskiDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0009-0006-1664-761X
Alberto G ContiDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0003-0725-337X
Jie YangDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0001-9157-0532
Sarah N LauderDivision of Infection and Immunity/System Immunity University Research Institute, Cardiff University, Cardiff CF14 4XN, UK.ORCID 0000-0003-2561-6277
Mathew ClementDivision of Infection and Immunity/System Immunity University Research Institute, Cardiff University, Cardiff CF14 4XN, UK.ORCID 0000-0002-9280-5281
Ian R HumphreysDivision of Infection and Immunity/System Immunity University Research Institute, Cardiff University, Cardiff CF14 4XN, UK.
James DooleyDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0003-3154-4708
Oliver BurtonDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0003-3884-7373
Adrian ListonDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0002-6272-4085
Marco AlloisioDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.ORCID 0000-0002-1415-5439
Emanuele VoulazDepartment of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Milan, Italy.ORCID 0000-0002-9091-6797
Jean LanghorneFrancis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Klaus OkkenhaugDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0002-9432-4051
Enrico LugliLaboratory of Translational Immunology, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy.
Rahul RoychoudhuriDepartment of Pathology, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QP, UK.ORCID 0000-0002-5392-1853
University of Cambridge · GBInstitute of Infection and Immunity · CAHumanitas University · ITIRCCS Humanitas Research Hospital · ITBabraham Institute · GBLa Jolla Institute for Immunology · USThe Francis Crick Institute · GB
Funding
Medical Research Council MR/S024468/2Medical Research Council MR/W018454/1Wellcome Trust
Abstract
Regulatory T (T
Indexed as
NeoplasmsT-Lymphocytes, RegulatoryAnimalsForkhead Transcription FactorsHumansImmunotherapyInterleukin-10MiceForkhead Transcription FactorsInterleukin-10
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.