Evidence map›Paper›PMID 38099997›Full record

SynthesisCurrent urology reports2024

Assessment of Prostate and Bladder Cancer Genomic Biomarkers Using Artificial Intelligence: a Systematic Review.

Andrey Bazarkin, Andrey Morozov, Alexander Androsov, Harun Fajkovic, Juan Gomez Rivas, Nirmish Singla, Svetlana Koroleva, Jeremy Yuen-Chun Teoh, Andrei V Zvyagin, Shahrokh François Shariat and 2 more

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Current urology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 9 countries.

Andrey BazarkinInstitute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.
Andrey MorozovInstitute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.
Alexander AndrosovDepartment of Pediatric Surgery, Division of Pediatric Urology and Andrology, Sechenov University, Moscow, Russia.
Harun FajkovicDepartment of Urology and Comprehensive Cancer Center, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Juan Gomez RivasDepartment of Urology, Clinico San Carlos University Hospital, Madrid, Spain.
Nirmish SinglaSchool of Medicine, Brady Urological Institute, Johns Hopkins Medicine, Baltimore, MD, USA.
Svetlana KorolevaClinical Institute for Children Health Named After N.F. Filatov, Sechenov University, Moscow, Russia.
Jeremy Yuen-Chun TeohDepartment of Surgery, S.H. Ho Urology Centre, The Chinese University of Hong Kong, Hong Kong, China.
Andrei V ZvyaginInstitute of Molecular Theranostics, Sechenov University, Moscow, Russia.
Shahrokh François ShariatDepartment of Urology and Comprehensive Cancer Center, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.
Bhaskar SomaniDepartment of Urology, University Hospital Southampton, Southampton, United Kingdom.
Dmitry EnikeevInstitute for Urology and Reproductive Health, Sechenov University, Moscow, Russia. dvenikeev@gmail.com.
Sechenov University · RUChinese University of Hong Kong · CNCity Clinical Hospital No15 named. O. M. Filatova · RUHospital Clínico San Carlos · ESJohns Hopkins Medicine · USKarl Landsteiner Society · ATMolecular Theranostics (United States) · USUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Jordan · JO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe aim of the systematic review is to assess AI's capabilities in the genetics of prostate cancer (PCa) and bladder cancer (BCa) to evaluate target groups for such analysis as well as to assess its prospects in daily practice. RECENT

findingsIn total, our analysis included 27 articles: 10 articles have reported on PCa and 17 on BCa, respectively. The AI algorithms added clinical value and demonstrated promising results in several fields, including cancer detection, assessment of cancer development risk, risk stratification in terms of survival and relapse, and prediction of response to a specific therapy. Besides clinical applications, genetic analysis aided by the AI shed light on the basic urologic cancer biology. We believe, our results of the AI application to the analysis of PCa, BCa data sets will help to identify new targets for urological cancer therapy. The integration of AI in genomic research for screening and clinical applications will evolve with time to help personalizing chemotherapy, prediction of survival and relapse, aid treatment strategies such as reducing frequency of diagnostic cystoscopies, and clinical decision support, e.g., by predicting immunotherapy response. These factors will ultimately lead to personalized and precision medicine thereby improving patient outcomes.

Indexed as

ProstateUrinary Bladder NeoplasmsArtificial IntelligenceBiomarkersHumansMaleNeoplasm Recurrence, LocalRecurrenceBiomarkersArtificial intelligenceBladder cancerDifferentially expressed genesGenomicsProstate cancer

Identifiers

PMID38099997
OpenAlexW4389789059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.