Evidence map›Paper›PMID 38099847›Full record

ReviewAmerican journal of physiology. Heart and circulatory physiology2024

Sex as a biological variable for cardiovascular physiology.

Merry L Lindsey, Charlotte W Usselman, Crystal M Ripplinger, Jason R Carter, Kristine Y DeLeon-Pennell

Open access · greenAbstract readReview
In one paragraph

Review in American journal of physiology. Heart and circulatory physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Assessing health in aging male and female mice: does cardiac function dictate frailty or physical resilience?The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  5. Article
  6. Article
  7. Sex-specific effects of mild kidney dysfunction on vascular function in midlife and older adults.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  8. Progress on incorporating sex as a biological variable in cardiovascular research.American journal of physiology. Heart and circulatory physiology · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 2 countries.

Merry L LindseySchool of Graduate Studies, Meharry Medical College, Nashville, Tennessee, United States.ORCID 0000-0002-4090-0391
Charlotte W UsselmanCardiovascular Health and Autonomic Regulation Laboratory, Department of Kinesiology and Physical Education, McGill University, Montreal, Quebec, Canada.ORCID 0000-0002-0803-8690
Crystal M RipplingerDepartment of Pharmacology, UC Davis School of Medicine, Davis, California, United States.ORCID 0000-0002-9908-4106
Jason R CarterRobbins College of Health and Human Sciences, Baylor University, Waco, Texas, United States.ORCID 0000-0001-7350-6537
Kristine Y DeLeon-PennellDivision of Cardiology, Department of Medicine, School of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States.ORCID 0000-0002-9647-6112
Baylor University · USMcGill University · CAMedical University of South Carolina · USMeharry Medical College · USUniversity of California, Davis · US

Funding

Project 3 (Mercola)P01HL141084 · NHLBI · STANFORD UNIVERSITY · PI Joseph C. Wu · 2019 to 2026
$21.1M
The Role of Adrenergic Stimulation in ArrhythmogenesisR01HL111600 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Crystal May Ripplinger · 2012 to 2026
$7.1M
Sex differences in cardiac autonomic remodeling after myocardial infarctionR01HL170626 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Crystal May Ripplinger, Marmar Vaseghi · 2024 to 2026
$2.1M
Short Course In Transferable Skills Training (SHIFT) ProgramR25GM151274 · NIGMS · MEHARRY MEDICAL COLLEGE · PI MERRY L. LINDSEY, Pius N Nde · 2023 to 2026
$1.9M
Alcohol and Neurovascular Control in HumansR01AA024892 · NIAAA · MONTANA STATE UNIVERSITY - BOZEMAN · PI CARTER, JASON R · 2017 to 2021
$1.8M
Neutrophil Polarization Following Myocardial InfarctionI01BX000505 · VA · VETERANS HEALTH ADMINISTRATION · PI LINDSEY, MERRY L. · 2009 to 2024
–
Innate-like CD8+ T-cells facilitate in cardiac remodeling post-MII01BX005848 · VA · RALPH H JOHNSON VA MEDICAL CENTER · PI Kristine Y DeLeon-Pennell · 2023 to 2026
–
BLRD VA I01 BX000505BLRD VA I01 BX005848NHLBI NIH HHS P01 HL141084NHLBI NIH HHS R01 HL111600NHLBI NIH HHS R01 HL170626NIAAA NIH HHS R01 AA024892NIGMS NIH HHS R25 GM151274
6 · The paper itself

Abstract

There have been ongoing efforts by federal agencies and scientific communities since the early 1990s to incorporate sex and/or gender in all aspects of cardiovascular research. Scientific journals provide a critical function as change agents to influence transformation by encouraging submissions for topic areas, and by setting standards and expectations for articles submitted to the journal. As part of ongoing efforts to advance sex and gender in cardiovascular physiology research, the

Indexed as

HeartInflammationCardiovascular Physiological PhenomenaFemaleHumansMaleReproducibility of ResultsResearch DesignUnited Statescardiovasculargenderreproducibilityrigorsex

Identifiers

PMID38099847
PMCPMC11219053
OpenAlexW4389783099

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.