Evidence map›Paper›PMID 38099828›Full record

ReviewRadiology. Imaging cancer2024

High-Intensity Focused Ultrasound Surgery for Tumor Ablation: A Review of Current Applications.

Alessandro De Maio, Giulia Alfieri, Monica Mattone, Pejman Ghanouni, Alessandro Napoli

Abstract readReview
In one paragraph

Review in Radiology. Imaging cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. Stimuli-Responsive Materials for Biomedical Applications.Advanced materials (Deerfield Beach, Fla.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alessandro De MaioFrom the Department of Radiological, Pathological, and Oncological Sciences, Sapienza University of Rome, viale Regina Elena 324, 00100 Rome, Italy (A.D.M., G.A., M.M., A.N.); and Department of Radiology, Stanford University, Stanford, Calif (P.G.).ORCID 0000-0003-3553-8671
Giulia AlfieriFrom the Department of Radiological, Pathological, and Oncological Sciences, Sapienza University of Rome, viale Regina Elena 324, 00100 Rome, Italy (A.D.M., G.A., M.M., A.N.); and Department of Radiology, Stanford University, Stanford, Calif (P.G.).ORCID 0000-0001-9016-0574
Monica MattoneFrom the Department of Radiological, Pathological, and Oncological Sciences, Sapienza University of Rome, viale Regina Elena 324, 00100 Rome, Italy (A.D.M., G.A., M.M., A.N.); and Department of Radiology, Stanford University, Stanford, Calif (P.G.).ORCID 0000-0001-9204-1608
Pejman GhanouniFrom the Department of Radiological, Pathological, and Oncological Sciences, Sapienza University of Rome, viale Regina Elena 324, 00100 Rome, Italy (A.D.M., G.A., M.M., A.N.); and Department of Radiology, Stanford University, Stanford, Calif (P.G.).ORCID 0000-0002-6393-0964
Alessandro NapoliFrom the Department of Radiological, Pathological, and Oncological Sciences, Sapienza University of Rome, viale Regina Elena 324, 00100 Rome, Italy (A.D.M., G.A., M.M., A.N.); and Department of Radiology, Stanford University, Stanford, Calif (P.G.).ORCID 0000-0001-8337-7652

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of cancer with alternative approaches is a matter of clinical interest worldwide. High-intensity focused ultrasound (HIFU) surgery is a noninvasive technique performed under US or MRI guidance. The most studied therapeutic uses of HIFU involve thermal tissue ablation, demonstrating both palliative and curative potential. However, concurrent mechanical bioeffects also provide opportunities in terms of augmented drug delivery and immunosensitization. The safety and efficacy of HIFU integration with current cancer treatment strategies are being actively investigated in managing primary and secondary tumors, including cancers of the breast, prostate, pancreas, liver, kidney, and bone. Current primary HIFU indications are pain palliation, complete ablation of localized earlystage tumors, or debulking of unresectable late-stage cancers. This review presents the latest HIFU applications, from investigational to clinically approved, in the field of tumor ablation.

Indexed as

Hyperthermia, InducedNeoplasmsUltrasonic Surgical ProceduresDrug Delivery SystemsHumansLiverMaleAssessmentInterventional-BodyInterventional-MSKMR ImagingOncologyTechnologyTumor ResponseUltrasoundUltrasound–High Intensity Focused (HIFU)

Identifiers

PMID38099828
PMCPMC10825716

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.