Evidence map›Paper›PMID 38099657›Full record

ReviewApplied and environmental microbiology2024

Wastewater surveillance for bacterial targets: current challenges and future goals.

Sarah E Philo, Kara B De León, Rachel T Noble, Nicolette A Zhou, Rashed Alghafri, Itay Bar-Or, Amanda Darling, Nishita D'Souza, Oumaima Hachimi, Devrim Kaya and 17 more

Abstract readReview
In one paragraph

Review in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Wastewater Surveillance for Group APathogens (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Sarah E PhiloDepartment of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame, Notre Dame, Indiana, USA.ORCID 0000-0002-9894-0425
Kara B De LeónSchool of Biological Sciences, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0000-0002-2499-5650
Rachel T NobleDepartment of Earth, Marine, and Environmental Sciences, University of North Carolina at Chapel Hill, Institute of Marine Sciences, Morehead City, North Carolina, USA.
Nicolette A ZhouDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-3854-376X
Rashed AlghafriInternational Center for Forensic Sciences, Dubai Police, Dubai, UAE.
Itay Bar-OrIsrael Ministry of Health, Jerusalem, Israel.
Amanda DarlingDepartment of Civil and Environmental Engineering, Virginia Tech, Blacksburg, Virginia, USA.
Nishita D'SouzaDepartment of Fisheries and Wildlife, Michigan State University, East Lansing, Michigan, USA.
Oumaima HachimiSchool of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, Oregon, USA.
Devrim KayaSchool of Public Health, San Diego State University, San Diego, California, USA.
Sooyeol KimDepartment of Civil and Environmental Engineering, University of California Berkeley, Berkeley, California, USA.
Katrin Gaardbo KuhnDepartment of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Blythe A LaytonClean Water Services, Hillsboro, Oregon, USA.
Cresten MansfeldtEnvironmental Engineering Program, University of Colorado Boulder, Boulder, Colorado, USA.
Bethany OcegueraDepartment of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame, Notre Dame, Indiana, USA.
Tyler S RadnieckiSchool of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, Oregon, USA.
Jeffrey L RamDepartment of Physiology, Wayne State University School of Medicine, Detroit, Michigan, USA.
Lauren P SaundersCeres Nanosciences, Manassas, Virginia, USA.
Abhilasha ShresthaEnvironmental and Occupational Health Sciences Division, University of Illinois Chicago School of Public Health, Chicago, Illinois, USA.
Lauren B StadlerCivil and Environmental Engineering, Rice University, Houston, Texas, USA.ORCID 0000-0001-7469-1981
Joshua A SteeleDepartment of Microbiology, Southern California Coastal Research Project, Costa Mesa, California, USA.ORCID 0000-0001-8023-8956
Bradley S StevensonEarth and Planetary Science, Northwestern University, Evanston, Illinois, USA.
Jason R VogelSchool of Civil Engineering and Environmental Science, University of Oklahoma, Norman, Oklahoma, USA.
Kyle BibbyDepartment of Civil and Environmental Engineering and Earth Sciences, University of Notre Dame, Notre Dame, Indiana, USA.ORCID 0000-0003-3142-6090
Alexandria B BoehmDepartment of Civil and Environmental Engineering, Stanford University, Stanford, California, USA.ORCID 0000-0002-8162-5090
Rolf U HaldenSchool of Sustainable Engineering and the Built Environment, Arizona State University, Tempe, Arizona, USA.ORCID 0000-0001-5232-7361
Jeseth Delgado VelaDepartment of Civil and Environmental Engineering, Duke University, Durham, North Carolina, USA.ORCID 0000-0001-6171-4400

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Hazel B Nichols · 2001 to 2026
$36.3M
Improved scalability, sensitivity, and interpretability of pathogen detection, including SARS-CoV-2, in wastewater using high-throughput, highly multiplexed digital array PCR technologyU01DA053899 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NOBLE, RACHEL TODD · 2021 to 2022
$1.7M
National Science Foundation (NSF) 2202361NIDA NIH HHS U01 DA053899NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Wastewater-based epidemiology (WBE) expanded rapidly in response to the COVID-19 pandemic. As the public health emergency has ended, researchers and practitioners are looking to shift the focus of existing wastewater surveillance programs to other targets, including bacteria. Bacterial targets may pose some unique challenges for WBE applications. To explore the current state of the field, the National Science Foundation-funded Research Coordination Network (RCN) on Wastewater Based Epidemiology for SARS-CoV-2 and Emerging Public Health Threats held a workshop in April 2023 to discuss the challenges and needs for wastewater bacterial surveillance. The targets and methods used in existing programs were diverse, with twelve different targets and nine different methods listed. Discussions during the workshop highlighted the challenges in adapting existing programs and identified research gaps in four key areas: choosing new targets, relating bacterial wastewater data to human disease incidence and prevalence, developing methods, and normalizing results. To help with these challenges and research gaps, the authors identified steps the larger community can take to improve bacteria wastewater surveillance. This includes developing data reporting standards and method optimization and validation for bacterial programs. Additionally, more work is needed to understand shedding patterns for potential bacterial targets to better relate wastewater data to human infections. Wastewater surveillance for bacteria can help provide insight into the underlying prevalence in communities, but much work is needed to establish these methods.IMPORTANCEWastewater surveillance was a useful tool to elucidate the burden and spread of SARS-CoV-2 during the pandemic. Public health officials and researchers are interested in expanding these surveillance programs to include bacterial targets, but many questions remain. The NSF-funded Research Coordination Network for Wastewater Surveillance of SARS-CoV-2 and Emerging Public Health Threats held a workshop to identify barriers and research gaps to implementing bacterial wastewater surveillance programs.

Indexed as

GoalsPandemicsBacteriaHumansSARS-CoV-2WastewaterWastewater-Based Epidemiological MonitoringWastewaterbacteriawastewater-based epidemiologywastewater surveillance

Identifiers

PMID38099657
PMCPMC10807411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.