Evidence map›Paper›PMID 38099617›Full record

ArticleMicrobiology spectrum2024

Detecting horizontal gene transfer among microbiota: an innovative pipeline for identifying co-shared genes within the mobilome through advanced comparative analysis.

Jana Schwarzerova, Michal Zeman, Vladimir Babak, Katerina Jureckova, Marketa Nykrynova, Margaret Varga, Wolfram Weckwerth, Monika Dolejska, Valentine Provaznik, Ivan Rychlik and 1 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Jana SchwarzerovaDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic.
Michal ZemanVeterinary Research Institute , Brno, Czech Republic.
Vladimir BabakVeterinary Research Institute , Brno, Czech Republic.
Katerina JureckovaDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic.
Marketa NykrynovaDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic.
Margaret VargaDepartment of Biology, University of Oxford , Oxford, United Kingdom.
Wolfram WeckwerthMolecular Systems Biology (MOSYS), Department of Functional and Evolutionary Ecology, University of Vienna , Vienna, Austria.
Monika DolejskaCentral European Institute of Technology, University of Veterinary Sciences Brno , Brno, Czech Republic.
Valentine ProvaznikDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic.
Ivan RychlikVeterinary Research Institute , Brno, Czech Republic.
Darina CejkovaDepartment of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology , Brno, Czech Republic.ORCID 0000-0002-6989-6330
Brno University of Technology · CZVeterinary Research Institute · CZUniversity of Vienna · ATMasaryk University · CZUniversity of Oxford · GBUniversity of Veterinary Sciences Brno · CZ

Funding

Czech Science Foundation GA22-16786SInternal Grant Agency of the University of Veterinary Sciences Brno 206/2023/FVHE
6 · The paper itself

Abstract

Horizontal gene transfer (HGT) is a key driver in the evolution of bacterial genomes. The acquisition of genes mediated by HGT may enable bacteria to adapt to ever-changing environmental conditions. Long-term application of antibiotics in intensive agriculture is associated with the dissemination of antibiotic resistance genes among bacteria with the consequences causing public health concern. Commensal farm-animal-associated gut microbiota are considered the reservoir of the resistance genes. Therefore, in this study, we identified known and not-yet characterized mobilized genes originating from chicken and porcine fecal samples using our innovative pipeline followed by network analysis to provide appropriate visualization to support proper interpretation.

Indexed as

Gene Transfer, HorizontalMicrobiotaAnimalsAnti-Bacterial AgentsBacteriaGenes, BacterialGenome, BacterialSwineAnti-Bacterial Agentsanimal microbiomegenome evolutiongut microbiotahorizontal gene transfermobile genetic elementsmobilomeresistance genes

Identifiers

PMID38099617
PMCPMC10782964
OpenAlexW4389801138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.