Evidence map›Paper›PMID 38099534›Full record

Trial reportReviews on recent clinical trials2024

Comparison of the Effects of Govarcin Herbal Capsule and Metoclopramide for Alleviating Gastrointestinal Symptoms in Patients with Functional Dyspepsia: A Randomized Double-blind Clinical Trial.

Majid Asghari, Sajjad Ahmadpour, Mikaeil Molazadeh, Mohammad Mehdi Jafari, Ahmad Hormati, Mohammad Reza Pashaei, Yousef Mohammadpour, Mohammad Amin Habibi, Abolfazl Mohammadbeigi, Seyed Mahmoud Eshagh Hoseini

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Reviews on recent clinical trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Majid AsghariDepartment of Persian Medicine, School of Persian Medicine, Spiritual Health Research Center, Qom University of Medical Sciences, Qom, Iran.ORCID 0000-0003-1155-3172
Sajjad AhmadpourPatient Safety Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran.ORCID 0000-0003-4321-874X
Mikaeil MolazadehDepartment of Medical Physics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Mohammad Mehdi JafariDepartment of Persian Medicine, School of Persian Medicine, Spiritual Health Research Center, Qom University of Medical Sciences, Qom, Iran.
Ahmad HormatiAssociate Professor of Gastroentrology and Hepatology, Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases Research Institute, Shariati Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID 0000-0002-1322-1318
Mohammad Reza PashaeiPatient Safety Research Center, Clinical Research Institute, Urmia University of Medical Sciences, Urmia, Iran.ORCID 0000-0001-9603-8529
Yousef MohammadpourAssistant Professor of Medical Education, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran.
Mohammad Amin HabibiIranian Tissue bank and Research Center, Gene, Cell and Tissue Institute, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Abolfazl MohammadbeigiDepartment of Biostatistics and Epidemiology, School of Health Research Center for Environmental Pollutants, Qom University of Medical Sciences, Qom, Iran.ORCID 0000-0002-3142-6413
Seyed Mahmoud Eshagh HoseiniGastroenterology and Liver Research Center of Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Qom University of Medical Science and Health Services · IRUrmia University · IRSarem Cell Research Center · IRShariati Hospital · IRTabriz University of Medical Sciences · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFunctional dyspepsia (FD) is felt as a discomfort or pain on the center line or upper abdomen. In this study, we aimed to compare the effects of Govarcin herbal capsule and Metoclopramide for alleviating gastrointestinal symptoms in patients with FD.

methodsTotally, 106 patients enrolled in a double-blind, clinical trial study. The participants had FD and were divided into two groups receiving Govarcin and Metoclopramide by block randomization. The patients were treated for four weeks, taking one Govarcin capsule or Metoclopramide tablet after each meal. The rate of improvement in patients was assessed by mitigation of clinical symptoms, including epigastric pain, fullness, discomfort, nausea, vomiting and heartburn. Also, before and after intervention, we used Nepin questionnaire and ROME III. SPSS statistics 25 software was used for data analyzing.

resultsClinical symptom score changes between Govarcin and Metoclopramide patients' groups showed that there was no significant difference in any of the clinical symptom scores (except for heartburn,

conclusionGovarcin herbal capsule can be used to remedy symptoms in patients with FD. It seems that Govarcin is as effective as Metoclopramide in fighting symptoms of FD as no significant difference in efficacy has been demonstrated between them.

Indexed as

DyspepsiaMetoclopramideAdultCapsulesDouble-Blind MethodDrugs, Chinese HerbalFemaleHumansMaleMiddle AgedTreatment OutcomeCapsulesDrugs, Chinese HerbalMetoclopramidefunctional dyspepsiaGovarcinheartburn.MetoclopramideNepean scorevomiting

Identifiers

PMID38099534
OpenAlexW4389803629

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.