ArticleAnalytical methods : advancing methods and applications2024
Method validation for (ultra)-trace element concentrations in urine for small sample volumes in large epidemiological studies: application to the population-based epidemiological multi-ethnic study of atherosclerosis (MESA).
Article in Analytical methods : advancing methods and applications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 14 citations in OpenAlex.
- Associations of drinking water and urinary uranium with incident diabetes among U.S. adults: The Multi-Ethnic Study of Atherosclerosis and the Strong Heart Family Study.Environmental research · 2026Article
- Metal and metal mixture biomarkers across three U.S. cohorts: MASALA, MESA-LA, and Strong Heart Family Study.Journal of exposure science & environmental epidemiology · 2026Article
- Biomonitoring of nutritional and toxic elements in raw and cooked rice in the Health Effects of Arsenic Longitudinal Study, Bangladesh.Ecotoxicology and environmental safety · 2026Article
- The role of coronary artery calcification in metal-related cardiovascular disease.Environment international · 2026Article
- Associations Between Urinary Metal Levels and Incident Heart Failure: A Multi-Cohort Analysis.JACC. Heart failure · 2025Article
- Geographic and Sociodemographic Differences in Cadmium Exposure in the Multi-Ethnic Study of Atherosclerosis (MESA).Exposure and health · 2025Article
- Uranium exposure and kidney tubule biomarkers in the Multi-Ethnic Study of Atherosclerosis (MESA).Environmental research · 2025Article
- Urinary Metal Levels, Cognitive Test Performance, and Dementia in the Multi-Ethnic Study of Atherosclerosis.JAMA network open · 2024Article
- Arsenic speciation analysis in human urine for long term epidemiological studies: The Multi-Ethnic Study of Atherosclerosis (MESA).Environmental research · 2024Article
- Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis.Journal of the American College of Cardiology · 2024Article
- Association of Urinary Metals With Cardiovascular Disease Incidence and All-Cause Mortality in the Multi-Ethnic Study of Atherosclerosis (MESA).Circulation · 2024Article
- Tampons as a source of exposure to metal(loid)s.Environment international · 2024Article
- Urinary Metal Levels and Coronary Artery Calcification: Longitudinal Evidence in the Multi-Ethnic Study of Atherosclerosis (MESA).medRxiv : the preprint server for health sciences · 2023Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Analysis of essential and non-essential trace elements in urine has emerged as a valuable tool for assessing occupational and environmental exposures, diagnosing nutritional status and guiding public health and health care intervention. Our study focused on the analysis of trace elements in urine samples from the Multi-Ethnic Study of Atherosclerosis (MESA), a precious resource for health research with limited sample volumes. Here we provide a comprehensive and sensitive method for the analysis of 18 elements using only 100 μL of urine. Method sensitivity, accuracy, and precision were assessed. The analysis by inductively coupled plasma mass spectrometry (ICP-MS) included the measurement of antimony (Sb), arsenic (As), barium (Ba), cadmium (Cd), cesium (Cs), cobalt (Co), copper (Cu), gadolinium (Gd), lead (Pb), manganese (Mn), molybdenum (Mo), nickel (Ni), selenium (Se), strontium (Sr), thallium (Tl), tungsten (W), uranium (U), and zinc (Zn). Further, we reported urinary trace element concentrations by covariates including gender, ethnicity/race, smoking and location. The results showed good accuracy and sensitivity of the ICP-MS method with the limit of detections rangings between 0.001 μg L
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