Evidence map›Paper›PMID 38099441›Full record

ReviewCirculation. Arrhythmia and electrophysiology2024

Clinical Management of Brugada Syndrome: Commentary From the Experts.

Michael J Cutler, Lee L Eckhardt, Elizabeth S Kaufman, Elena Arbelo, Elijah R Behr, Pedro Brugada, Marina Cerrone, Lia Crotti, Carlo deAsmundis, Michael H Gollob and 18 more

Open access · greenAbstract readReview
In one paragraph

Review in Circulation. Arrhythmia and electrophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Magnetic field based investigation of Brugada syndrome.European biophysics journal : EBJ · 2026
    Article
  2. Review
  3. Article
  4. Zebrafish as a Model System for Brugada Syndrome.Reviews in cardiovascular medicine · 2024
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 11 countries.

Michael J Cutler *Intermountain Heart Institute, Intermountain Medical Center, Salt Lake City, UT (M.J.C.).ORCID 0000-0001-9498-7472
Lee L Eckhardt *Cellular and Molecular Arrhythmia Research Program, Division of CVM, Department of Medicine, University of Wisconsin-Madison (L.L.E.).ORCID 0000-0001-5792-064X
Elizabeth S Kaufman *Heart and Vascular Center, MetroHealth Campus, Case Western Reserve University, Cleveland, OH (E.S.K.).ORCID 0000-0002-7042-0612
Elena ArbeloArrhythmia Section, Cardiology Department, Hospital Clínic, Universitat de Barcelona (E.A.).ORCID 0000-0003-0424-6393
Elijah R BehrCardiovascular Clinical Academic Group, Cardiology Section, St. George's, University of London and St. George's University Hospitals NHS Foundation Trust (E.R.B.).ORCID 0000-0002-8731-2853
Pedro BrugadaCardiovascular Division, UZ Brussel-VUB, Belgium (P.B.).ORCID 0000-0003-3172-6106
Marina CerroneNew York Univ Grossman School of Medicine, Leon H. Charney Division of Cardiology (M.C.).ORCID 0000-0002-6122-9939
Lia CrottiDepartment of Medicine and Surgery, University of Milano-Bicocca (L.C.).ORCID 0000-0001-8739-6527
Carlo deAsmundisHeart Rhythm Management Center, Postgraduate Program in Cardiac Electrophysiology and Pacing, Universitair Ziekenhuis Brussel-Vrije Universiteit Brussel, European Reference Networks Guard-Heart, Belgium (C.D.).ORCID 0000-0001-9351-0760
Michael H GollobPeter Munk Cardiac Center, Division of Cardiology, Toronto General Hospital, University Health Network, Canada (M.H.G.).ORCID 0000-0003-0242-5208
Minoru HorieDepartment of Cardiovascular Medicine, Shiga University of Medical Science, Ohtsu, Japan (M.H.).ORCID 0000-0002-9029-2339
David T HuangUniversity of Rochester Medical Center, NY (D.T.H.).ORCID 0000-0002-9165-7643
Andrew D KrahnCenter for Cardiovascular Innovation, Division of Cardiology, University of British Columbia, Vancouver, Canada (A.D.K.).ORCID 0000-0002-7982-1586
Barry LondonDivision of Cardiovascular Medicine, Department of Internal Medicine and Abboud Cardiovascular Research Center, University of Iowa Carver College of Medicine, Iowa City (B.L.).ORCID 0000-0003-1506-3947
Steven A LubitzDemoulas Center for Cardiac Arrhythmias, Massachusetts General Hospital, Boston (S.A.L.).ORCID 0000-0002-9599-4866
Judith A MackallDepartment of Medicine, Division of Cardiology, University Hospitals Harrington Heart and Vascular Institute, Case Western Reserve University School of Medicine, Cleveland, OH (J.A.M.).ORCID 0000-0003-4324-0226
Koonlawee NademaneeCenter of Excellence in Arrhythmia Research, Department of Medicine, Faculty of Medicine, Chulalongkorn University (K.N.).ORCID 0000-0001-8139-0343
Marco V PerezStanford Center for Inherited Cardiovascular Diseases, Stanford University, CA (M.V.P.).ORCID 0000-0003-2746-0202
Vincent ProbstUniversité Nantes, CHU Nantes, CNRS, INSERM, Service de Cardiologie, l'institut du thorax, Nantes, France (V.P.).ORCID 0000-0002-5492-8619
Dan M RodenDepartments of Medicine, Pharmacology and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN (D.M.R.).ORCID 0000-0002-6302-0389
Frederic SacherArrhythmia Department, Bordeaux University Hospital, IHU LIRYC, Pessac, France (F.S.).ORCID 0000-0001-8348-9320
Georgia Sarquella-BrugadaPediatric Arrhythmias, Inherited Cardiac Diseases and Sudden Death Unit, Hospital Sant Joan de Déu, Universitat de Barcelona (G.S.-B.).ORCID 0000-0002-6857-8904
Melvin M ScheinmanSection of Cardiac Electrophysiology, Division of Cardiology, University of California-San Francisco (M.M.S.).ORCID 0000-0001-6295-3753
Wataru ShimizuDepartment of Cardiovascular Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan (W.S.).ORCID 0000-0001-9941-8973
Benjamin ShoemakerDepartment of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN (B.S.).ORCID 0000-0001-6824-7155
Raymond W SyFaculty of Medicine and Heath, The University of Sydney (R.W.S.).ORCID 0000-0003-2984-1869
Atsuyuki WatanabeDepartment of Cardiology, National Hospital Organization Okayama Medical Center, Japan (A.W.).
Arthur A M WildeDepartment of Cardiology, University of Amsterdam (A.A.M.W.).ORCID 0000-0002-0528-0852
Vanderbilt University Medical Center · USAmsterdam University of Applied Sciences · NLCardiovascular Institute of the South · USCentre National de la Recherche Scientifique · FRCentro de Investigación en Red en Enfermedades Cardiovasculares · ESChulalongkorn University · THElectrophysiology and Heart Modeling Institute · FRHospital Sant Joan de Déu Barcelona · ESIntermountain Medical Center · USIRCCS Istituto Auxologico Italiano · ITMassachusetts General Hospital · USMetroHealth Medical Center · USNew York University · USNippon Medical School · JPOkayama Medical Center · JPShiga University of Medical Science · JPSt George’s University Hospitals NHS Foundation Trust · GBThe University of Sydney · AUTwitter (United States) · USUniversitair Ziekenhuis Brussel · BE

Funding

Systematically mapping variant effects for cardiovascular genesR01HL164675 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ASHLEY, EUAN A, RODEN, DAN M · 2022 to 2025
$8.1M
SUMOylation of Voltage-Gated Sodium Channels In Neuronal Hyperexcitability of Alzheimer’s DementiaR01HL115955 · NHLBI · UNIVERSITY OF IOWA · PI IRANI, KAIKOBAD J., LONDON, BARRY · 2013 to 2023
$5.4M
Genomics of Cardiac ArrhythmiasR01HL139731 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS · 2018 to 2022
$3.3M
Functional Genomics of Cardiac Sodium Channel VariantsR01HL149826 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RODEN, DAN M · 2020 to 2023
$2.9M
Using Electrocardiogram Genetics to Inform Arrhythmia RiskR01HL157635 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS, MIRSHAHI, TOORAJ · 2022 to 2025
$2.9M
CLINICAL AND MOLECULAR ANALYSIS OF THE BRUGADA SYNDROMER01HL062300 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SABA, SAMIR FAWZI · 1999 to 2011
$2.8M
Genetic Modulators of Sudden DeathR01HL077398 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LONDON, BARRY · 2004 to 2008
$2.6M
Transcriptional Regulation of KCNH2R01HL141343 · NHLBI · UNIVERSITY OF KENTUCKY · PI DELISLE, BRIAN P · 2019 to 2022
$2.3M
Deep Mutational Scanning and Functional Analysis of Repolarization DeterminantsR01HL163987 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI ECKHARDT, LEE LOCHBAUM · 2022 to 2025
$1.6M
KCNJ2-Induced Arrhythmia Mechanisms in CPVT and Heart Failure.R01HL139738 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI ECKHARDT, LEE LOCHBAUM · 2018 to 2021
$1.5M
NHLBI NIH HHS R01 HL062300NHLBI NIH HHS R01 HL077398NHLBI NIH HHS R01 HL115955NHLBI NIH HHS R01 HL139731NHLBI NIH HHS R01 HL139738NHLBI NIH HHS R01 HL141343NHLBI NIH HHS R01 HL149826NHLBI NIH HHS R01 HL157635NHLBI NIH HHS R01 HL163987NHLBI NIH HHS R01 HL164675
6 · The paper itself

Abstract

Although there is consensus on the management of patients with Brugada Syndrome with high risk for sudden cardiac arrest, asymptomatic or intermediate-risk patients present clinical management challenges. This document explores the management opinions of experts throughout the world for patients with Brugada Syndrome who do not fit guideline recommendations. Four real-world clinical scenarios were presented with commentary from small expert groups for each case. All authors voted on case-specific questions to evaluate the level of consensus among the entire group in nuanced diagnostic and management decisions relevant to each case. Points of agreement, points of controversy, and gaps in knowledge are highlighted.

Indexed as

Brugada SyndromeHeart ArrestConsensusDeath, Sudden, CardiacElectrocardiographyHumansBrugada Syndromesudden cardiac arrestsyncopeventricular fibrillation

Identifiers

PMID38099441
PMCPMC10824563
OpenAlexW4389788020

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.