ArticleNeurobiology of pain (Cambridge, Mass.)
Monoclonal antibodies against GFRα3 are efficacious against evoked hyperalgesic and allodynic responses in mouse join pain models but, one of these, REGN5069, was not effective against pain in a randomized, placebo-controlled clinical trial in patients with osteoarthritis pain.
Selin Somersan-Karakaya et al.PubMed ↗Full text ↗Publisher ↗
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