Evidence map›Paper›PMID 38099251›Full record

ArticleRSC advances2023

Dual anticancer and antibacterial activity of fluorescent naphthoimidazolium salts.

Dung Ngoc Tran, Thi Thuy Hang Hoang, Sondavid Nandanwar, Vuong Thi Thanh Xuan Ho, Van Thong Pham, Huy Duc Vu, Xuan Ha Nguyen, Huy Trung Nguyen, Trang Van Nguyen, Thuy Kieu Van Nguyen and 4 more

Open access · goldAbstract read
In one paragraph

Article in RSC advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Facile Synthesis ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Dung Ngoc TranFaculty of Chemistry, Hanoi National University of Education Hanoi Vietnam.
Thi Thuy Hang HoangDepartment of Chemistry, Soongsil University Seoul 06978 South Korea.
Sondavid NandanwarEco-friendly New Materials Research Center, Korea Research Institute of Chemical Technology 141 Gajeong-ro, Yuseong-gu Daejeon City Republic of Korea.
Vuong Thi Thanh Xuan HoFaculty of Pharmacy, Dong A University Danang Vietnam.
Van Thong PhamR&D Center, Vietnam Education and Technology Transfer JSC Cau Giay Hanoi Vietnam.
Huy Duc VuDepartment of Radiology, School of Medicine, Daegu Catholic University Daegu 42472 Korea.
Xuan Ha NguyenInstitute of Natural Products Chemistry, Vietnam Academy of Science and Technology 18 Hoang Quoc Viet, Cau Giay Hanoi Vietnam.
Huy Trung NguyenInstitute for Tropical Technology, Vietnam Academy of Science and Technology 18 Hoang Quoc Viet, Cau Giay Hanoi Vietnam ptchung@itt.vast.vn.
Trang Van NguyenInstitute for Tropical Technology, Vietnam Academy of Science and Technology 18 Hoang Quoc Viet, Cau Giay Hanoi Vietnam ptchung@itt.vast.vn.
Thuy Kieu Van NguyenIndustry 4.0 Convergence Bionics Engineering, Pukyong National University Busan 48513 Korea slee@pknu.ac.kr.
Dai Lam TranInstitute for Tropical Technology, Vietnam Academy of Science and Technology 18 Hoang Quoc Viet, Cau Giay Hanoi Vietnam ptchung@itt.vast.vn.
Myeongkee ParkDepartment of Chemistry, Pukyong National University Busan 48513 Korea.
Songyi LeeIndustry 4.0 Convergence Bionics Engineering, Pukyong National University Busan 48513 Korea slee@pknu.ac.kr.ORCID https://orcid.org/0000-0002-8788-6056
Thanh Chung PhamInstitute for Tropical Technology, Vietnam Academy of Science and Technology 18 Hoang Quoc Viet, Cau Giay Hanoi Vietnam ptchung@itt.vast.vn.ORCID https://orcid.org/0000-0001-5196-0931
Institute for Tropical TechnologyHanoi National University of Education · VNPukyong National University · KRDaegu Catholic University · KRKorea Research Institute of Chemical Technology · KRSoongsil University · KRUniversity of Da Nang · VNVietnam Academy of Science and Technology · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer has emerged as a significant global health challenge, ranking as the second leading cause of death worldwide. Moreover, cancer patients frequently experience compromised immune systems, rendering them susceptible to bacterial infections. Combining anticancer and antibacterial properties in a single drug could lead to improved overall treatment outcomes and patient well-being. In this context, the present study focused on a series of hydrophilic naphthoimidazolium salts with donor groups (NI-R), aiming to create dual-functional agents with antibacterial and anticancer activities. Among these compounds, NI-TPA demonstrated notable antibacterial activity, particularly against drug-resistant bacteria, with MIC value of 7.8 μg mL

Identifiers

PMID38099251
PMCPMC10719908
OpenAlexW4389737063

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.