Evidence map›Paper›PMID 38099244›Full record

ArticleAdvanced genetics (Hoboken, N.J.)2023

Insight into the Causal Relationship between Gut Microbiota and Back Pain: A Two Sample Bidirectional Mendelian Randomization Study.

Jingni Hui, Yujing Chen, Chun'e Li, Yifan Gou, Ye Liu, Ruixue Zhou, Meijuan Kang, Chen Liu, Bingyi Wang, Panxing Shi and 8 more

Open access · goldAbstract read
In one paragraph

Article in Advanced genetics (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 1 institution in 1 country.

Jingni HuiKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.ORCID https://orcid.org/0009-0004-2391-3184
Yujing ChenKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Chun'e LiKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Yifan GouKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Ye LiuKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Ruixue ZhouKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Meijuan KangKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Chen LiuKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Bingyi WangKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Panxing ShiKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Shiqiang ChengKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Xuena YangKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Chuyu PanKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Yumeng JiaKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Bolun ChengKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Huan LiuKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Yan WenKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.
Feng ZhangKey Laboratory of Trace Elements and Endemic Diseases of National Health and Family Planning Commission School of Public Health Health Science Center Xi'an Jiaotong University Xi'an 71006 P. R. China.ORCID https://orcid.org/0000-0003-1339-5956
National Health and Family Planning Commission · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Observational studies have shown that alterations in gut microbiota composition are associated with low back pain. However, it remains unclear whether the association is causal. To reveal the causal association between gut microbiota and low back pain, a two-sample bidirectional Mendelian randomization (MR) analysis is performed. The inverse variance weighted regression (IVW) is performed as the principal MR analysis. MR-Egger and Weighted Median is further conducted as complementary analysis to validate the robustness of the results. Finally, a reverse MR analysis is performed to evaluate the possibility of reverse causation. The inverse variance weighted (IVW) method suggests that

Indexed as

causal relationshipgut microbiotalow back painMendelian randomization

Identifiers

PMID38099244
PMCPMC10716053
OpenAlexW4388509411

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.