Evidence map›Paper›PMID 38099075›Full record

ArticleEuropean heart journal. Case reports2023

Cardiogenic shock after 5-fluorouracil administration: a case report and literature review.

Lowie Vanoverbeke, Holvoet Wouter, D'Heygere François, Elegeert Ivan

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal. Case reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Lowie VanoverbekeDepartment of Cardiology, AZ Groeninge, President Kennedylaan 4, Kortrijk 8500, Belgium.ORCID https://orcid.org/0000-0002-6887-8405
Holvoet WouterDepartment of Cardiology, AZ Groeninge, President Kennedylaan 4, Kortrijk 8500, Belgium.
D'Heygere FrançoisDepartment of Gastroenterology, AZ Groeninge, Kortrijk, Belgium.
Elegeert IvanDepartment of Cardiology, AZ Groeninge, President Kennedylaan 4, Kortrijk 8500, Belgium.
AZ Groeninge · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cardiogenic shock is a rare adverse event of 5-fluorouracil (5-FU) administration. Because of its rare entity, little is known about epidemiologic and clinical features of 5-FU-induced cardiogenic shock, and recommendations about specific treatment are missing. Case summary: We present a case of cardiogenic shock and ventricular arrhythmia due to 5-FU-induced toxic cardiomyopathy treated with vasopressor and inotropic drugs in combination with intra-aortic balloon pump. Because of persistent haemodynamic instability, veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and Impella were implanted as a bridge to recovery. Systolic function recovered completely and the patient was weaned successfully. Discussion: This case demonstrates toxic cardiomyopathy as a rare and potentially lethal cardiac adverse event of 5-FU administration. This case emphasizes the importance of mechanical support as bridging therapy to recovery of cardiac function.

Indexed as

5-FluorouracilCardiogenic shockCardiotoxicityCase reportVA-ECMO

Identifiers

PMID38099075
PMCPMC10720692
OpenAlexW4389703329

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.