Evidence map›Paper›PMID 38098889›Full record

ArticleBioMed research international2023

Structural Dynamics of P-Rex1 Complexed with Natural Leads Establishes the Protein as an Attractive Target for Therapeutics to Suppress Cancer Metastasis.

Alaa R Hameed, Sama Fakhri Ali, Sarah M S Alsallameh, Ziyad Tariq Muhseen, Nahlah Makki Almansour, Naif ALSuhaymi, Mahdi H Alsugoor, Khaled S Allemailem

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Alaa R HameedDepartment of Medical Laboratory Techniques, School of Life Sciences, Dijlah University College, Baghdad, Iraq.
Sama Fakhri AliDepartment of Anesthesia Techniques, School of Life Sciences, Dijlah University College, Baghdad, Iraq.
Sarah M S AlsallamehMinistry of Higher Education and Scientific Research, Gilgamesh Ahliya University College, College of Health and Medical Techniques, Department of Medical Laboratories Techniques, Baghdad, Iraq.ORCID https://orcid.org/0000-0003-1801-653X
Ziyad Tariq MuhseenDepartment of Pharmacy, Al-Mustaqbal University College, Hillah, Babylon 51001, Iraq.ORCID https://orcid.org/0000-0001-7660-6461
Nahlah Makki AlmansourDepartment of Biology, College of Science, University of Hafr Al Batin, Hafr Al Batin 31991, Saudi Arabia.
Naif ALSuhaymiDepartment of Emergency Medical Services, Faculty of Health Sciences, AlQunfudah, Umm Al-Qura University, Mecca 21912, Saudi Arabia.
Mahdi H AlsugoorDepartment of Emergency Medical Services, Faculty of Health Sciences, AlQunfudah, Umm Al-Qura University, Mecca 21912, Saudi Arabia.
Khaled S AllemailemDepartment of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraydah 51452, Saudi Arabia.ORCID https://orcid.org/0000-0002-6486-9835
Dijlah University College · IQUmm al-Qura University · SAMinistry of Higher Education and Scientific Research · IQQassim University · SAUniversity of Hafr Al-Batin · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phosphatidylinositol 3,4,5-trisphosphate- (PIP3-) dependent Rac exchanger 1 (P-Rex1) functions as Rho guanine nucleotide exchange factor and is activated by synergistic activity of G

Indexed as

Molecular Dynamics SimulationNeoplasmsHumansMale

Identifiers

PMID38098889
PMCPMC10721353
OpenAlexW4389426662

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.