Evidence map›Paper›PMID 38098837›Full record

ArticleFrontiers in public health2023

High perceived stress in patients on opioid agonist therapies during rapid transitional response to the COVID-19 pandemic in Ukraine.

Samy J Galvez, Frederick L Altice, Anna Meteliuk, Roman Ivasiy, Eteri Machavariani, Scott O Farnum, Tetiana Fomenko, Zahedul Islam, Lynn M Madden

Erratum issuedAbstract read
In one paragraph

Article in Frontiers in public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Samy J GalvezYale School of Medicine, Section of Infectious Diseases, New Haven, CT, United States.
Frederick L AlticeYale School of Medicine, Section of Infectious Diseases, New Haven, CT, United States.
Anna MeteliukAPT Foundation, New Haven, CT, United States.
Roman IvasiyYale School of Medicine, Section of Infectious Diseases, New Haven, CT, United States.
Eteri MachavarianiYale School of Medicine, Section of Infectious Diseases, New Haven, CT, United States.
Scott O FarnumAlliance for Public Health of Ukraine, Kyiv, Ukraine.
Tetiana FomenkoAPT Foundation, New Haven, CT, United States.
Zahedul IslamAPT Foundation, New Haven, CT, United States.
Lynn M MaddenAlliance for Public Health of Ukraine, Kyiv, Ukraine.

Funding

Expanding Medication Assisted Therapy in Ukraine (ExMAT)R01DA033679 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2012 to 2021
$6.4M
Integrating Addiction Treatment and HIV Services into Primary Care Clinics in UkraineR01DA043125 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2016 to 2021
$4.4M
The prefrontal cortex in salience and control in cocaine addiction: phFMRI studyR01DA023579 · NIDA · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI GOLDSTEIN, RITA Z · 2008 to 2012
$2.8M
Integrating Treatment for Mental Disorders in Methadone Clinics in UkraineR01DA045384 · NIDA · UKRAINIAN INSTITUTE ON PUBLIC HEALTH POLICY · PI DVORIAK, SERGII · 2021 to 2022
$884k
NIDA NIH HHS R01 DA023579NIDA NIH HHS R01 DA033679NIDA NIH HHS R01 DA043125NIDA NIH HHS R01 DA045384
6 · The paper itself

Abstract

Background: The COVID-19 pandemic resulted in marked disruptions in healthcare delivery in Ukraine related to emergency guidance in response to treating opioid use disorder (OUD). Patients with OUD, a group with high levels of comorbid medical and psychiatric disorders, and prescribed opioid agonist therapies (OAT) were rapidly shifted to take-home dosing if they were deemed clinically stable. The impact of these shifts on patient stress and related substance use during the pandemic, however, is unknown. Methods: In early May 2020, 269 randomly selected OAT patients in Ukraine were surveyed to assess their stress level and substance use using the validated Perceived Stress Scale and examined correlates of severe perceived stress. Results: Overall, 195 (72.5%) met criteria for moderate to severe levels of stress, which was independently correlated with having started OAT within the past 12 months (aOR: 1.33; 95%CI: 1.15-1.55), living in a large metropolitan area (aOR: 1.31; 95%CI: 1.18-1.46), having been asked by others to share their medication (aOR: 1.13; 95%CI: 1.02-1.25), and having an increase of over 10 min in transportation time to get to treatment (aOR: 1.16; 95%CI: 1.04-1.29). Twenty seven (10%) patients felt at high risk of relapse, while 24 (8.9%) patients reported purchasing drugs. Conclusion: During a time of great uncertainty soon after emergency guidance to the COVID-19 pandemic, there was extraordinary high levels of perceived stress reported. In response to emergency guidance, OAT patients should be screened for perceived stress and certain subgroups should be targeted for additional psychosocial support.

Indexed as

COVID-19Opioid-Related DisordersSubstance Abuse, IntravenousAnalgesics, OpioidHumansPandemicsPsychological TestsSelf ReportStress, PsychologicalUkraineAnalgesics, OpioidbuprenorphineCOVID-19methadoneopioid agonist therapiesstressUkraine

Identifiers

PMID38098837
PMCPMC10720365

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.