Evidence map›Paper›PMID 38098806›Full record

ArticleFrontiers in physiology2023

Spatial mapping of ectonucleotidase gene expression in the murine urinary bladder.

Mafalda S L Aresta Branco, Brian A Perrino, Violeta N Mutafova-Yambolieva

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Dysregulation of CD39/Ectonucleoside Triphosphate Diphosphohydrolase 1 Causes Urinary Bladder Dysfunction with Abnormal Smooth Muscle Contractility.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mafalda S L Aresta BrancoDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, United States.
Brian A PerrinoDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, United States.
Violeta N Mutafova-YambolievaDepartment of Physiology and Cell Biology, University of Nevada Reno School of Medicine, Reno, NV, United States.
University of Nevada, Reno · US

Funding

Transgenic Animal Genotyping and Phenotyping CoreP20GM130459 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Andreia Nunes · 2019 to 2026
$20.3M
Urothelial Purinergic Signaling During Bladder FillingR01DK119482 · NIDDK · UNIVERSITY OF NEVADA RENO · PI Violeta N. Mutafova-Yambolieva · 2020 to 2026
$3.3M
NIDDK NIH HHS R01 DK119482NIGMS NIH HHS P20 GM130459
6 · The paper itself

Abstract

Purinergic signaling is important for normal bladder function, as it is thought to initiate the voiding reflex and modulate smooth muscle tone. The availability of adenine nucleotides and nucleosides (aka purines) at receptor sites of various cell types in the bladder wall is regulated by ectonucleotidases (ENTDs). ENTDs hydrolyze purines such as adenosine 5'-triphosphate (ATP) and adenosine 5'-diphosphate (ADP) with varying preference for the individual substrate. Therefore, the end effect of extracellular purines may depend significantly on the type of ENTD that is expressed in close proximity to the target cells. ENTDs likely have distinct cellular associations, but the specific locations of individual enzymes in the bladder wall are poorly understood. We used RNAscope™, an RNA

Indexed as

ATPbladdernucleotidasespurinergic signalingRNAscope

Identifiers

PMID38098806
PMCPMC10719621
OpenAlexW4389204781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.