Evidence map›Paper›PMID 38098719›Full record

ArticleChemical science2023

Native mass spectrometry of proteoliposomes containing integral and peripheral membrane proteins.

Yun Zhu, Sangho D Yun, Tianqi Zhang, Jing-Yuan Chang, Lauren Stover, Arthur Laganowsky

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Capturing RAS oligomerization on a membrane.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  5. TREK2 Lipid Binding Preferences Revealed by Native Mass Spectrometry.Journal of the American Society for Mass Spectrometry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yun ZhuDepartment of Chemistry, Texas A&M University College Station TX 77843 USA ALaganowsky@chem.tamu.edu.
Sangho D YunDepartment of Chemistry, Texas A&M University College Station TX 77843 USA ALaganowsky@chem.tamu.edu.ORCID https://orcid.org/0000-0003-2456-4575
Tianqi ZhangDepartment of Chemistry, Texas A&M University College Station TX 77843 USA ALaganowsky@chem.tamu.edu.
Jing-Yuan ChangDepartment of Chemistry, Texas A&M University College Station TX 77843 USA ALaganowsky@chem.tamu.edu.
Lauren StoverDepartment of Chemistry, Texas A&M University College Station TX 77843 USA ALaganowsky@chem.tamu.edu.
Arthur LaganowskyDepartment of Chemistry, Texas A&M University College Station TX 77843 USA ALaganowsky@chem.tamu.edu.ORCID https://orcid.org/0000-0001-5012-5547
Texas A&M University · US

Funding

Native Mass Spectrometry Guided Structural Biology CenterRM1GM149374 · NIGMS · OHIO STATE UNIVERSITY · PI Vicki H. Wysocki · 2023 to 2026
$5.0M
Innovative Native Ion Mobility Approaches for Transformational Measurements in Structural BiologyR01GM138863 · NIGMS · TEXAS A&M UNIVERSITY · PI CLOWERS, BRIAN, LAGANOWSKY, ARTHUR D · 2020 to 2023
$1.2M
Developing new tools to probe membrane protein-lipid interactions for biomedical applicationsR01GM139876 · NIGMS · TEXAS A&M UNIVERSITY · PI LAGANOWSKY, ARTHUR D · 2021 to 2024
$1.2M
NIGMS NIH HHS R01 GM138863NIGMS NIH HHS R01 GM139876NIGMS NIH HHS RM1 GM149374
6 · The paper itself

Abstract

Cellular membranes are critical to the function of membrane proteins, whether they are associated (peripheral) or embedded (integral) within the bilayer. While detergents have contributed to our understanding of membrane protein structure and function, there remains challenges in characterizing protein-lipid interactions within the context of an intact membrane. Here, we developed a method to prepare proteoliposomes for native mass spectrometry (MS) studies. We first use native MS to detect the encapsulation of soluble proteins within liposomes. We then find the peripheral G

Identifiers

PMID38098719
PMCPMC10718073
OpenAlexW4388861909

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.