Evidence map›Paper›PMID 38098649›Full record

ArticleInfluenza and other respiratory viruses2023

Impact of antiviral therapy on short- and long-term outcomes of patients with chronic obstructive pulmonary disease after influenza infection.

Christopher Wallick, Tu My To, Stephan Korom, Henry Masters, Ning Wu, Dalia Moawad, Nicola A Hanania

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Christopher WallickGenentech, Inc. South San Francisco California USA.ORCID 0000-0003-2521-5895
Tu My ToGenentech, Inc. South San Francisco California USA.
Stephan KoromF. Hoffmann-La Roche Ltd. Basel Switzerland.
Henry MastersGenentech, Inc. South San Francisco California USA.
Ning WuGenentech, Inc. South San Francisco California USA.
Dalia MoawadGenentech, Inc. South San Francisco California USA.
Nicola A HananiaSection of Pulmonary, Critical Care and Sleep Medicine Baylor College of Medicine Houston Texas USA.ORCID 0000-0003-3087-9530
Baylor College of Medicine · USRoche (Switzerland) · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Respiratory complications often accompany influenza in patients with chronic obstructive pulmonary disease (COPD). In this retrospective study, we quantified the impact of antiviral therapy on exacerbations, healthcare resource utilization (HRU), and costs in patients with COPD across 5 influenza seasons. Methods: Using claims data from US MarketScan® databases, we identified patients with COPD who had an influenza diagnosis during the 2012-2016 influenza seasons. Patients who received a neuraminidase inhibitor within 48 h of diagnosis ( Results: Antiviral-treated patients had a significantly lower frequency of COPD-related outcomes than untreated patients during all periods (exacerbations: 10.4% vs 18.2% [month 1] and 17.7% vs 24.2% [months 2-13]; inpatient visit: 2.5% vs 7.9% [month 1] and 3.8% vs 6.7% [months 2-13]; Conclusions: Antiviral treatment in patients with COPD and influenza is associated with significantly lower HRU and costs in the postinfection month and for an entire year following infection compared with untreated patients.

Indexed as

Influenza, HumanPneumoniaPulmonary Disease, Chronic ObstructiveAntiviral AgentsBronchodilator AgentsHumansRetrospective StudiesAntiviral AgentsBronchodilator Agentsantiviralschronic obstructive pulmonary diseasecostshealthcare resource utilizationinfluenzalong‐term

Identifiers

PMID38098649
PMCPMC10719080
OpenAlexW4389738783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.