Evidence map›Paper›PMID 38098612›Full record

ArticleChem catalysis2022

Imprinted Polymeric Nanoparticles as Artificial Enzymes for Ester Hydrolysis at Room Temperature and pH 7.

M D Arifuzzaman, Ishani Bose, Foroogh Bahrami, Yan Zhao

Abstract read
In one paragraph

Article in Chem catalysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

M D ArifuzzamanDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, U.S.A.
Ishani BoseDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, U.S.A.
Foroogh BahramiDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, U.S.A.
Yan ZhaoDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, U.S.A.

Funding

Artificial Glycosidase with Controlled SelectivityR01GM138427 · NIGMS · IOWA STATE UNIVERSITY · PI ZHAO, YAN · 2020 to 2023
$1.3M
NIGMS NIH HHS R01 GM138427
6 · The paper itself

Abstract

Natural esterases hydrolyze esters under physiological pHs but chemists often have to use strongly acidic or basic conditions for the same hydrolysis. We report synthetic nanoparticle catalysts that hydrolyze nonactivated alkyl esters at room temperature and neutral pH, with enzyme-like catalytic mechanisms and exquisite substrate selectivity. Unlike natural enzymes that denature easily at elevated temperatures, the synthetic catalysts become more active at higher temperatures.

Indexed as

active siteartificial enzymecooperative catalysiselectrostaticmicellemolecular imprinting

Identifiers

PMID38098612
PMCPMC10720975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.