Evidence map›Paper›PMID 38098459›Full record

ArticleACS chemical biology2023

Stapled Phd Peptides Inhibit Doc Toxin Induced Growth Arrest in

Dennis J Worm, Grzegorz J Grabe, Guilherme V de Castro, Sofya Rabinovich, Ian Warm, Kira Isherwood, Sophie Helaine, Anna Barnard

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Dennis J WormDepartment of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London W12 0BZ, U.K.
Grzegorz J GrabeDepartment of Microbiology, Harvard Medical School, 4 Blackfan Circle, Boston, Massachusetts 02115, United States.
Guilherme V de CastroDepartment of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London W12 0BZ, U.K.
Sofya RabinovichDepartment of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London W12 0BZ, U.K.
Ian WarmDepartment of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London W12 0BZ, U.K.ORCID 0009-0009-2695-0403
Kira IsherwoodDepartment of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London W12 0BZ, U.K.
Sophie HelaineDepartment of Microbiology, Harvard Medical School, 4 Blackfan Circle, Boston, Massachusetts 02115, United States.
Anna BarnardDepartment of Chemistry, Molecular Sciences Research Hub, Imperial College London, 82 Wood Lane, London W12 0BZ, U.K.ORCID 0000-0002-1327-3417
Imperial College London · GBHarvard University · US

Funding

The physiological activation and consequences of Toxin-Antitoxin systems in SalmonellaR01AI155552 · NIAID · HARVARD MEDICAL SCHOOL · PI HELAINE, SOPHIE · 2021 to 2025
$2.5M
NIAID NIH HHS R01 AI155552Wellcome Trust
6 · The paper itself

Abstract

Bacterial toxin inhibition is a promising approach to overcoming antibiotic failure. In

Indexed as

AntitoxinsBacterial ToxinsAnti-Bacterial AgentsBacterial ProteinsPeptidesSalmonellaAnti-Bacterial AgentsAntitoxinsBacterial ProteinsBacterial ToxinsPeptides

Identifiers

PMID38098459
PMCPMC10728895
OpenAlexW4388862823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.