Evidence map›Paper›PMID 38097744›Full record

ArticleGenes and immunity2024

Looking to the future of antibody genetics: resolving the roles of immunoglobulin diversity in gene regulation, function, and immunity.

Corey T Watson, Oscar L Rodriguez, Eric Engelbrecht, Yana Safonova, Wayne A Marasco, Melissa L Smith

Abstract readComment
PubMed Publisher
In one paragraph

Article in Genes and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Corey T WatsonDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA. corey.watson@louisville.edu.ORCID 0000-0001-7248-8787
Oscar L RodriguezDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA.
Eric EngelbrechtDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA.
Yana SafonovaComputer Science and Engineering Department, Huck Institutes of the Life Sciences, Penn State University, State College, PA, USA.
Wayne A MarascoDepartment of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-3764-4611
Melissa L SmithDepartment of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA.

Funding

An ethnically diverse genomic reference resource for the human heavy and light chain immunoglobulin lociR24AI138963 · NIAID · UNIVERSITY OF LOUISVILLE · PI Melissa Laird Smith, Corey Taylor Watson · 2018 to 2026
$5.5M
Population level characterization of human immunoglobulin heavy chain germline variants with impacts on variability in the Ab repertoire of healthy adultsR21AI142590 · NIAID · UNIVERSITY OF LOUISVILLE · PI MARASCO, WAYNE A., WATSON, COREY TAYLOR · 2019 to 2020
$477k
Division of Intramural Research, National Institute of Allergy and Infectious Diseases (Division of Intramural Research of the NIAID) R21AI142590Division of Intramural Research, National Institute of Allergy and Infectious Diseases (Division of Intramural Research of the NIAID) R24AI138963
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntibodiesAntibody DiversityGenes, ImmunoglobulinAntibodies

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.