Evidence map›Paper›PMID 38097726›Full record

ArticleScientific reports2023

Cognitive impairment experienced by Chinese breast cancer survivors.

Dan Chen, Lynette Mackenzie, Syeda Zakia Hossain, Jing-Xin Wang, Ping-Lan Jiang, Yuanxiao Wang, Lanhui Qin, Jun Zhen, Jie Jia

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Prevalence of cancer-related cognitive impairment among patients with nasopharyngeal carcinoma: a cross-sectional study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Dan ChenDepartment of Rehabilitation Medicine, Jing'an District Central Hospital of Shanghai, Shanghai, China.
Lynette MackenzieDiscipline of Occupational Therapy, School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, 2006, Australia. Lynette.Mackenzie@sydney.edu.au.ORCID 0000-0002-1597-2051
Syeda Zakia HossainDiscipline of Behavioural Sciences, School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, 2006, Australia.ORCID 0000-0002-8847-3464
Jing-Xin WangDepartment of Rehabilitation Medicine, Zhengzhou Central Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Ping-Lan JiangDepartment of Breast Surgery, Xiangya Hospital of Central South University, Changsha, China.
Yuanxiao WangDepartment of Breast Surgery, Yunnan Cancer Hospital, Yunnan, China.
Lanhui QinDepartment of Rehabilitation, the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
Jun ZhenDepartment of Rehabilitation, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong, China.
Jie JiaDepartment of Rehabilitation Medicine, Jing'an District Central Hospital of Shanghai, Shanghai, China.
Fudan University · CNThe University of Sydney · AUCentral South University · CNSun Yat-sen University · CNThe People's Hospital of Guangxi Zhuang Autonomous Region · CNZhengzhou Central Hospital · CN

Funding

National atural Science Major Research Program Integrated Program of China 91948302National Key Research and Development Program of China 2018YFC2002300National Natural Science Innovation Research Group Program of China 82021002
6 · The paper itself

Abstract

To identify cognitive function in Chinese breast cancer survivors. Research questions were: is cognitive function was associated with breast cancer and/or chemotherapy treatment and/or psychological functioning:? and did women with breast cancer experience more cognitive and psychological issues than age-matched women without cancer? Breast cancer survivors with chemotherapy (n = 106, mean age = 50.2 ± 9.5), breast cancer survivors without chemotherapy (n = 100, mean age = 50.5 ± 10.0) and matched healthy controls (n = 96, mean age = 47.9 ± 9.1) completed a battery of cognitive and psychosocial functioning. Demographic characteristics were also collected. The Perceived Cognitive Impairment score for cancer groups was significantly higher than for the healthy group (p = 0.04), but not between the cancer groups. Processing speed was significantly slower in the cancer groups than in the healthy group (both p < 0.001), but not between the cancer groups. Age, living status and education were significantly associated with the FACT-Cog (all p < 0.05). The correlations between the FACT-Cog score and BSI score were strong (r = 0.60 p < 0.01), and between the HADS anxiety and depression scales were strong (r = 0.53 and 0.50, p < 0.01) but correlations were weaker between performance based cognitive tests and measures of psychological functioning. Breast cancer groups indicated more cognitive impairment and reduced psychological functioning compared to the healthy group. However, there was no differences between the breast cancer groups. Chinese breast cancer survivors experienced excess cognitive impairment not associated with usual ageing. Assessment and intervention to address cognitive impairment should be made available to breast cancer survivors.

Indexed as

Breast NeoplasmsCancer SurvivorsCognitive DysfunctionAdultChinaCognitionFemaleHumansMiddle AgedQuality of LifeSurvivors

Identifiers

PMID38097726
PMCPMC10721869
OpenAlexW4389728576

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.