ArticleNature communications2023
Site-selective chemical reactions by on-water surface sequential assembly.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Article
- On-Water Surface Synthesis of 2D Conjugated Metal-Organic Framework Films With Controllable Layer Orientation Enabling High-Performance Chemiresistive Sensing.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- SMAIS: a universal platform for the on-water surface synthesis of two-dimensional polymer crystals.Nature protocols · 2026Review
- Reevaluating Anomalous Electric Fields at the Air-Water Interface: A Surface-Specific Spectroscopic Survey.Journal of the American Chemical Society · 2025Article
- On-liquid surface synthesis of diyne-linked two-dimensional polymer crystals.Nature communications · 2025Article
- Homologous heteropolyaromatic covalent organic frameworks for enhancing photocatalytic hydrogen peroxide production and aerobic oxidation.Nature communications · 2025Article
- High-Performance Phototransistor Based on a 2D Polybenzimidazole Polymer.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Surfactant-Assisted Construction of Covalent Organic Frameworks.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Synthesis of crystalline two-dimensional conjugated polymers through irreversible chemistry under mild conditions.Nature communications · 2025Article
- Designer topological-single-atom catalysts with site-specific selectivity.Nature communications · 2025Article
- Mimicking on-water surface synthesis through micellar interfaces.Nature communications · 2024Article
- On-Water Surface Synthesis of Two-Dimensional Polymer Membranes for Sustainable Energy Devices.Accounts of chemical research · 2024Article
Corrections and comments
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Authors and funding
17 authors at 7 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Controlling site-selectivity and reactivity in chemical reactions continues to be a key challenge in modern synthetic chemistry. Here, we demonstrate the discovery of site-selective chemical reactions on the water surface via a sequential assembly approach. A negatively charged surfactant monolayer on the water surface guides the electrostatically driven, epitaxial, and aligned assembly of reagent amino-substituted porphyrin molecules, resulting in a well-defined J-aggregated structure. This constrained geometry of the porphyrin molecules prompts the subsequent directional alignment of the perylenetetracarboxylic dianhydride reagent, enabling the selective formation of a one-sided imide bond between porphyrin and reagent. Surface-specific in-situ spectroscopies reveal the underlying mechanism of the dynamic interface that promotes multilayer growth of the site-selective imide product. The site-selective reaction on the water surface is further demonstrated by three reversible and irreversible chemical reactions, such as imide-, imine-, and 1, 3-diazole (imidazole)- bonds involving porphyrin molecules. This unique sequential assembly approach enables site-selective chemical reactions that can bring on-water surface synthesis to the forefront of modern organic chemistry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.