ArticleNature communications2023
Prediction and stratification of longitudinal risk for chronic obstructive pulmonary disease across smoking behaviors.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 28 citations in OpenAlex.
- Exposome-wide association study and predictive risk score for incident Alzheimer's disease and related dementias.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Effect of Socioeconomic Status on Lung Function in the Korean General Population.Journal of Korean medical science · 2026Article
- Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk prediction.Nature genetics · 2026Article
- Prevalence and Risk Factors of Chronic Obstructive Pulmonary Disease in Kazakhstan in a Nationwide Population-Based Epidemiological Study.International journal of chronic obstructive pulmonary disease · 2026Article
- Are Real-World Mobility Patterns Early Indicators of COPD Onset? Insights from Wrist-Worn Sensors.International journal of chronic obstructive pulmonary disease · 2026Article
- Predictive Value of Biological Age for All-Cause Mortality in Patients with COPD.International journal of chronic obstructive pulmonary disease · 2026Article
- Chronic Obstructive Pulmonary Disease in Never-Smokers-A Distinct Entity Within the COPD Spectrum.Life (Basel, Switzerland) · 2025Review
- Genetics and context for precision health in Greater Boston.Nature communications · 2025Article
- Pulmonary Emphysema: Current Understanding of Disease Pathogenesis and Therapeutic Approaches.Biomedicines · 2025Review
- Human Plasma Proteomics Links Modifiable Lifestyle Exposome to Disease Risk.medRxiv : the preprint server for health sciences · 2025Article
- Integrating exposomics into biomedicine.Science (New York, N.Y.) · 2025Article
- Circular RNAs as Biomarkers in the Diagnosis of Human Diseases.Advances in experimental medicine and biology · 2025Review
- Risk and Protective Factors of COPD Among Smokers: A Cross-Sectional Study Using NHANES Database.International journal of chronic obstructive pulmonary disease · 2025Article
- A comprehensive analysis of the impact of smoking on adverse clinical outcomes of steatotic liver diseases.Therapeutic advances in gastroenterology · 2025Article
- Machine learning approach to flare-up detection and clustering in chronic obstructive pulmonary disease (COPD) patients.Health information science and systems · 2024Article
- Multi-trait and multi-ancestry genetic analysis of comorbid lung diseases and traits improves genetic discovery and polygenic risk prediction.medRxiv : the preprint server for health sciences · 2024Article
- Exploring the genetics of airflow limitation in lung function across the lifespan - a polygenic risk score study.EClinicalMedicine · 2024Article
- Unveiling the Long-Term Lung Consequences of Smoking and Tobacco Consumption: A Narrative Review.Cureus · 2024Review
- Aspiring toward equitable benefits from genomic advances to individuals of ancestrally diverse backgrounds.American journal of human genetics · 2024Review
- The Role of Nutrition in the Development and Management of Chronic Obstructive Pulmonary Disease.Nutrients · 2024Review
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
Smoking is the leading risk factor for chronic obstructive pulmonary disease (COPD) worldwide, yet many people who never smoke develop COPD. We perform a longitudinal analysis of COPD in the UK Biobank to derive and validate the Socioeconomic and Environmental Risk Score which captures additive and cumulative environmental, behavioral, and socioeconomic exposure risks beyond tobacco smoking. The Socioeconomic and Environmental Risk Score is more predictive of COPD than smoking status and pack-years. Individuals in the highest decile of the risk score have a greater risk for incident COPD compared to the remaining population. Never smokers in the highest decile of exposure risk are more likely to develop COPD than previous and current smokers in the lowest decile. In general, the prediction accuracy of the Social and Environmental Risk Score is lower in non-European populations. While smoking status is often considered in screening COPD, our finding highlights the importance of other non-smoking environmental and socioeconomic variables.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.