Evidence map›Paper›PMID 38097360›Full record

ArticleOpen heart2023

Country and health expenditure are major predictors of withholding anticoagulation in atrial fibrillation patients at high risk of stroke.

Deborah M Siegal, Frederik H Verbrugge, Anne-Celine Martin, Saverio Virdone, John Camm, Karen Pieper, Bernard J Gersh, Shinya Goto, Alexander G G Turpie, Pantep Angchaisuksiri and 1 more

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In one paragraph

Article in Open heart, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Deborah M SiegalMedicine, Ottawa Hospital General Campus, Ottawa, Ontario, Canada drdebsiegal@gmail.com.ORCID 0000-0003-3806-3245
Frederik H VerbruggeVrije Universiteit Brussel, Brussel, Belgium.
Anne-Celine MartinCardiology, European Hospital Georges-Pompidou, Paris, Île-de-France, France.
Saverio VirdoneDepartment of Statistics, Thrombosis Research Institute, London, UK.
John CammCardiology, St George's Hospital, London, UK.
Karen PieperThrombosis Research Institute, London, UK.
Bernard J GershMayo Clinic, Rochester, Minnesota, USA.
Shinya GotoMedicine, Tokai University School of Medicine Graduate School of Medicine, Isehara, Japan.
Alexander G G TurpieMcMaster University, Hamilton, Ontario, Canada.
Pantep AngchaisuksiriMedicine, Mahidol University, Salaya, Nakhon Pathom, Thailand.
Keith A A FoxCardiology, University of Edinburgh and Royal Infirmary of Edinburgh, Edinburgh, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGuidelines for patients with atrial fibrillation (AF) at high thromboembolic risk recommend oral anticoagulants (OACs) for preventing stroke and systemic embolism (SE). The reasons for guideline non-adherence are still unclear.

aimThe aim is to identify clinical, demographic and non-patient characteristics associated with withholding OAC in patients with AF at high stroke risk.

methodsPatients in the Global Anticoagulant Registry in the FIELD-AF, newly diagnosed with AF between March 2010 and August 2016, and with CHA

resultsOf 40 416 eligible patients, 12 126 (30.0%) did not receive OACs at baseline. Globally, OAC prescription increased over time, from 60.4% in 2010-2011 to 74.7% in 2015-2016. Country of enrolment was the major predictor for OAC withholding (χ

conclusionsApproximately one out of three AF patients did not receive OAC, while eligible according to the guidelines. Country of enrolment was the major determinant of anticoagulation strategy, while higher country health expenditure was associated with lower likelihood of withholding anticoagulation.

Indexed as

Atrial FibrillationStrokeAgedAnticoagulantsHealth ExpendituresHumansRisk FactorsAnticoagulantsatrial fibrillationdelivery of health caremyocardial infarctionquality of health carestroke

Identifiers

PMID38097360
PMCPMC10729201

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.