Evidence map›Paper›PMID 38097269›Full record

ArticleBJGP open2024

Pharmacist-led interventions in optimising the use of oral anticoagulants in patients with atrial fibrillation in general practice in England: a retrospective observational study.

Raman Sharma, Syed Shahzad Hasan, Ishtiaq A Gilkar, Waheed F Hussain, Barbara R Conway, Muhammad Usman Ghori

Open access · goldAbstract read
In one paragraph

Article in BJGP open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Raman SharmaDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.
Syed Shahzad HasanDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.
Ishtiaq A GilkarLittle Horton Lane Medical Centre, Bradford, UK.
Waheed F HussainClarendon Medical Centre, Bradford, UK.
Barbara R ConwayDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.
Muhammad Usman GhoriDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK m.ghori@hud.ac.uk.
University of Huddersfield · GBClarendon College · USHorton General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOral anticoagulation (OAC) is the mainstay of treatment for the prevention of strokes in patients with atrial fibrillation (AF). Direct oral anticoagulants (DOACs) account for increasing OAC in patients with AF. However, prescribing DOACs for patients with established AF poses various challenges and general practice pharmacists may have an important role in supporting their management.

aimTo investigate the effectiveness of pharmacist-led interventions in general practice in optimising the use of OAC therapies in AF. DESIGN &

settingA retrospective observational study in general practices in Bradford.

methodThe data were collected retrospectively from 1 November 2018-31 December 2019 using electronic health record data. The data were analysed: 1) to identify patients with AF not on OAC; 2) to describe inappropriate DOAC prescriptions; and 3) to calculate HAS-BLED scores.

resultsOverall, 76.3% (

conclusionPharmacist-led interventions have successfully improved the use of OAC therapies in patients with AF, and effectively managed the bleeding risks and transition from VKA to DOAC therapy, in line with guidelines.

Indexed as

anticoagulationatrial fibrillationdirect oral anticoagulantsgeneral practicepharmacistsprescribing

Identifiers

PMID38097269
PMCPMC11300970
OpenAlexW4389742784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.