Evidence map›Paper›PMID 38096784›Full record

ArticleCell host & microbe2023

Bacterial antigens unleash tumor-targeting immunity.

Nina Boeck, Zlatko Trajanoski, Lorenzo Galluzzi

Open access · greenAbstract readComment
In one paragraph

Article in Cell host & microbe, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Nina BoeckDepartment of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA; Biocenter, Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria.
Zlatko TrajanoskiBiocenter, Institute of Bioinformatics, Medical University of Innsbruck, Innsbruck, Austria.
Lorenzo GalluzziDepartment of Radiation Oncology, Weill Cornell Medical College, New York, NY, USA; Sandra and Edward Meyer Cancer Center, New York, NY, USA; Caryl and Israel Englander Institute for Precision Medicine, New York, NY, USA. Electronic address: deadoc80@gmail.com.
Cornell University · USInnsbruck Medical University · ATUniversität Innsbruck · AT

Funding

Radiation Effect on Immune Cells and the MicrobiomeU54CA274291 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Encouse Golden · 2022 to 2026
$9.1M
Targeting the BCL2 immune checkpoint to enhance the immunostimulatory effects of radiation in breast cancerR01CA271915 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Lorenzo Galluzzi · 2023 to 2026
$2.9M
NCI NIH HHS R01 CA271915NCI NIH HHS U54 CA274291
6 · The paper itself

Abstract

The composition of the gut microbiome has been shown to influence disease outcome in patients with colorectal cancer (CRC). In a recent Nature Biotechnology article, Wang et al. demonstrate that killing CRC-associated bacteria with a liposomal antibiotic elicits CRC-targeting immune responses of therapeutic relevance as a consequence of epitope mimicry.

Indexed as

Colorectal NeoplasmsGastrointestinal MicrobiomeAntigens, BacterialEpitopesHumansImmunityAntigens, BacterialEpitopes

Identifiers

PMID38096784
PMCPMC11075005
OpenAlexW4389688124

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.