Evidence map›Paper›PMID 38096412›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Genetic and immune determinants of

Karthik Hullahalli, Katherine G Dailey, Yuko Hasegawa, Encarnacion Torres, Masataka Suzuki, Hailong Zhang, David W Threadgill, Victor M Navarro, Matthew K Waldor

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. HypervirulentMicrobiology spectrum · 2026
    Article
  2. Review
  3. Characterization ofInfection and drug resistance · 2026
    Article
  4. Review
  5. Article
  6. Advances in Single-Cell Sequencing for Infectious Diseases: Progress and Perspectives.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Temporal and spatial dynamics ofProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  13. Reverse transcriptase inhibitors prevent liver abscess formation duringProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  14. Innate immune responses yield tissue-specific bottlenecks that scale with pathogen dose.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Karthik HullahalliDepartment of Microbiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-3064-2090
Katherine G DaileyDepartment of Microbiology, Harvard Medical School, Boston, MA 02115.ORCID 0009-0004-7013-0932
Yuko HasegawaDepartment of Microbiology, Harvard Medical School, Boston, MA 02115.
Encarnacion TorresDepartment of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.
Masataka SuzukiDepartment of Microbiology, Harvard Medical School, Boston, MA 02115.
Hailong ZhangDepartment of Microbiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-4903-010X
David W ThreadgillDepartment of Cell Biology and Genetics, Texas A&M University, College Station, TX 76549.ORCID 0000-0003-3538-1635
Victor M NavarroDepartment of Medicine, Division of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115.ORCID 0000-0002-5799-219X
Matthew K WaldorDepartment of Microbiology, Harvard Medical School, Boston, MA 02115.ORCID 0000-0003-1843-7000
Brigham and Women's Hospital · USMitchell Institute · US

Funding

Vibrio cholerae intestinal colonization and vaccine developmentR01AI042347 · NIAID · TUFTS UNIVERSITY BOSTON · PI WALDOR, MATTHEW K · 1998 to 2025
$7.3M
Characterization of the role of the amygdala in reproductive functionR01HD099084 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI NAVARRO, VICTOR MANUEL · 2020 to 2024
$2.3M
Characterization of Kiss1 neurons as mediators of the reproductive regulation of energy balanceR01DK133760 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI NAVARRO, VICTOR MANUEL · 2022 to 2025
$2.2M
Hepatic survival and population dynamics of extraintestinal pathogenic Escherichia coliF31AI156949 · NIAID · HARVARD MEDICAL SCHOOL · PI HULLAHALLI, KARTHIK · 2021 to 2023
$111k
NIAID NIH HHS F31 AI156949NIAID NIH HHS R01 AI042347NICHD NIH HHS R01 HD099084NIDDK NIH HHS R01 DK133760
6 · The paper itself

Abstract

Systemic infections can yield distinct outcomes in different tissues. In mice, intravenous inoculation of

Indexed as

Escherichia coli InfectionsLiver AbscessAnimalsEscherichia coliFemaleImmunity, InnateLymphocytesMiceMice, Inbred C57BLToll-Like Receptor 4Toll-Like Receptor 4E. coliliver abscesssystemic infectionTLR4

Identifiers

PMID38096412
PMCPMC10743367
OpenAlexW4389722705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.