Evidence map›Paper›PMID 38096378›Full record

ReviewJournal of proteome research2024

Parsing 20 Years of Public Data by AI Maps Trends in Proteomics and Forecasts Technology.

Josiah J Green, Chase Grimm, Andre Fristo, Joseph Byrum, Neil L Kelleher

Abstract readReview
In one paragraph

Review in Journal of proteome research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Josiah J GreenConsilience, Inc., 36 Muzzey Street, Lexington, Massachusetts 02421, United States.
Chase GrimmConsilience, Inc., 36 Muzzey Street, Lexington, Massachusetts 02421, United States.
Andre FristoConsilience, Inc., 36 Muzzey Street, Lexington, Massachusetts 02421, United States.
Joseph ByrumConsilience, Inc., 36 Muzzey Street, Lexington, Massachusetts 02421, United States.ORCID 0009-0004-4928-5454
Neil L KelleherDepartments of Chemistry and Molecular Biosciences, the Chemistry of Life Processes Institute, and the Proteomics Center of Excellence, Northwestern University, Evanston, Illinois 60208, United States.ORCID 0000-0002-8815-3372

Funding

TR&D 7: Cell Specific ProteomicsP41GM108569 · NIGMS · NORTHWESTERN UNIVERSITY · PI KELLEHER, NEIL L · 2015 to 2024
$13.6M
Renewable and Specific Affinity Reagents for Mapping Proteoforms in Human TissuesUH3CA246635 · NCI · NORTHWESTERN UNIVERSITY · PI KELLEHER, NEIL L · 2019 to 2021
$1.4M
NCI NIH HHS UH3 CA246635NIGMS NIH HHS P41 GM108569
6 · The paper itself

Abstract

The trends of the last 20 years in biotechnology were revealed using artificial intelligence and natural language processing (NLP) of publicly available data. Implementing this "science-of-science" approach, we capture convergent trends in the field of proteomics in both technology development and application across the phylogenetic tree of life. With major gaps in our knowledge about protein composition, structure, and location over time, we report trends in persistent, popular approaches and emerging technologies across 94 ideas from a corpus of 29 journals in PubMed over two decades. New metrics for clusters of these ideas reveal the progression and popularity of emerging approaches like single-cell, spatial, compositional, and chemical proteomics designed to better capture protein-level chemistry and biology. This analysis of the proteomics literature with advanced analytic tools quantifies the Rate of Rise for a next generation of technologies to better define, quantify, and visualize the multiple dimensions of the proteome that will transform our ability to measure and understand proteins in the coming decade.

Indexed as

Artificial IntelligenceProteomicsPhylogenyProteomeTechnologyProteomeartificial intelligencechemical proteomicsconsilience (convergent evidence)data mininggenomicsliterature trendsnatural language processingpredictionproteinsproteoformsproteomicssingle-cell biologysingle molecule protein sequencingspatial biologystructural proteomics

Identifiers

PMID38096378
PMCPMC10874502

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.