ArticleJournal of cancer survivorship : research and practice2025
Longitudinal trajectories of depression and quality of life in a cohort of cancer survivors and individuals without cancer in Europe.
Article in Journal of cancer survivorship : research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.
- Changes in quality of life throughout the illness trajectory of older adults with cancer: a systematic review.The oncologist · 2025Pooled it
- In Silico Psycho-Oncology: Understanding Resilience Pathways in Breast Cancer-Determinants of Longitudinal Depression and Quality-of-Life Trajectories.Journal of personalized medicine · 2026Article
- Trajectories of health-related quality of life after cancer diagnosis in a cohort of Australian women: a longitudinal study.Health and quality of life outcomes · 2026Article
- Beyond survival: the hidden impact of depression on life after cancer.Journal of cancer survivorship : research and practice · 2026Article
- Chemotherapy and Persistent Depression in Older Mexican Cancer Survivors: Secondary Analysis of the Mexican Health and Aging Study.Cancer investigation · 2025Observational
- Anxiety and Depression Trajectories in Young Adults Up to 5 Years After Being Diagnosed With Cancer.Cancer medicine · 2025Article
- Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe long-term effects of cancer on psychological symptoms and quality of life (QoL) have been widely reported, but they were seldom examined over time compared to the general population.
aimsTo investigate trajectories of depression and QoL over time among cancer survivors compared to individuals without cancer throughout Europe and identify associated factors.
methodsData from five waves of the Survey of Health, Ageing and Retirement in Europe study were used. The study sample featured 1066 cancer survivors and 9655 individuals without cancer from 13 European countries. Group-based trajectory modeling was used to identify depression and QoL trajectories, and a linear mixed-effects model was used to characterize their correlates.
resultsFour depression trajectories-stable low, stable high, increasing, and decreasing-and four QoL trajectories were identified. All QoL trajectories were stable over time, but differed in their levels: low, low-medium, medium-high, and high. Depression and QoL trajectories were similar between cancer survivors and individuals without cancer. However, significantly more cancer survivors had high-depression and low-QoL trajectories. Further, better perceived health, activities of daily living, physical activity, and income adequacy levels were significantly associated with changes in depression and QoL levels over time.
conclusionsAlthough depression and QoL trajectories did not differ between cancer survivors and individuals without cancer, more cancer survivors were characterized by high-depression and low-QoL life trajectories. IMPLICATIONS FOR CANCER SURVIVORS: Providers should be aware and screen for cancer survivors with elevated depression and low QoL, and promote relevant psychosocial interventions. Modifiable factors associated with depression and QoL can be targets for cancer survivors' long-term care plans.
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