Evidence map›Paper›PMID 38095745›Full record

ArticleVeterinary research communications2024

Nodular pyogranulomatous panniculitis due to Leishmania infantum infection in a domestic ferret (Mustela putorius furo).

Jacobo Giner, Jordi Jiménez, Alex Gómez, Ana Rodríguez-Largo, Carles Juan-Sallés, Cristina Riera, Roser Fisa, Sergio Villanueva-Saz

Open access · hybridAbstract read
In one paragraph

Article in Veterinary research communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Jacobo Giner *Menescalia Veterinary Clinic, Ismael Merlo Actor, 5, Valencia, 46020, Spain.
Jordi Jiménez *Els Altres Veterinary Clinic, Carrer del Rosselló, 274, Barcelona, 08037, Spain.
Alex GómezAnimal Pathology Department, Veterinary Faculty, Universidad de Zaragoza, Miguel Servet 177, Zaragoza, 50013, Spain.
Ana Rodríguez-LargoAnimal Pathology Department, Veterinary Faculty, Universidad de Zaragoza, Miguel Servet 177, Zaragoza, 50013, Spain.
Carles Juan-SallésNoah's Path, Arquitecto Santiago Pérez Aracil 30 bajo (centro veterinario), Elche, 03203, Spain.
Cristina RieraFaculty of Pharmacy and Food Sciences, Universitat de Barcelona, Avda. Joan XXIII s/n, Barcelona, 08028, Spain.
Roser FisaFaculty of Pharmacy and Food Sciences, Universitat de Barcelona, Avda. Joan XXIII s/n, Barcelona, 08028, Spain.
Sergio Villanueva-SazAnimal Pathology Department, Veterinary Faculty, Universidad de Zaragoza, Miguel Servet 177, Zaragoza, 50013, Spain. svs@unizar.es.
Universidad de Zaragoza · ESUniversitat de Barcelona · ESMenescalia Centro Veterinario · ESNoah's Path · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leishmaniosis is a vector-borne disease caused by different Leishmania species and transmitted by phlebotomine sand flies under natural conditions in Europe. Scientific information related to Leishmania infantum in dogs is extensive, where less information is available in cats and other companion animals. Recently, first clinical cases of L.infantum infection in domestic ferrrets (Mustela putorius furo) have been described. However, clinical information on leishmaniosis in this species is limited A 15-month-old male neutered domestic ferret was presented with chronic weight loss and the presence of coalescent, erythematous and firm subcutaneous nodules in the ventral abdominal subcutis. A fine-needle aspiration of these nodules was performed and the cytological examination revealed a granulomatous inflammation with the presence of macrophages contained a number of oval organisms with an eccentric nucleus and pale cytoplasm, compatible with Leishmania spp. amastigotes compatible with Leishmania spp. amastigotes. The nodules were surgically excised and histological examination showed a severe multifocal pyogranulomatous panniculitis. Specific immunohistochemistry and qPCR for L. infantum from excised nodules were positive. Additionally, L. infantum was cultured and isolated from the nodules by a fine-needle aspiration. An in-house Western Blot test for L. infantum was performed in serum sample and a positive result was obtained. This is the first reported case of nodular pyogranulomatous panniculitis due to L. infantum infection in a domestic ferret. Further studies are necessary to determine the relevance of domestic ferrets in the transmission of leishmaniosis. The description of new clinical forms of the disease is important as it can assist veterinarians in identifying these new clinical presentations.

Indexed as

Cat DiseasesDog DiseasesLeishmania infantumLeishmaniasis, VisceralPanniculitisAnimalsCatsDogsFerretsImmunohistochemistryMaleFerretLeishmania infantumPanniculitisPyogranulomatousSpain

Identifiers

PMID38095745
PMCPMC10998802
OpenAlexW4389741794

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.