ArticleAging2023
Obesity, birth weight, and lifestyle factors for frailty: a Mendelian randomization study.
Article in Aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 13 citations in OpenAlex.
- Early-life exposure to tobacco smoke increase risk of frailty in adulthood: evidence from a large prospective cohort study.Journal of translational medicine · 2025Article
- Sedentary lifestyle, physical activity, and aging: evidence from genetic correlation and mendelian randomization.Aging clinical and experimental research · 2025Article
- Metformin reduces the risk of frailty: evidence from a Mendelian randomization study.Diabetology & metabolic syndrome · 2025Article
- A Longitudinal Study of the Bidirectional Temporal Dynamics Between Body Mass Index and Biological Aging.Journal of cachexia, sarcopenia and muscle · 2025Article
- Lifestyle, environment and other major determinants of frailty in older adults: a population-based study from the UK Biobank.Biogerontology · 2025Article
- Determinants and risk prediction models for frailty among community-living older adults in eastern China.Frontiers in public health · 2025Article
- Development and validation of nomograms to predict frailty-worsening trajectories among Chinese older adults.Frontiers in public health · 2025Article
- Association of visceral adiposity index and lipid accumulation product with frailty in U.S. adults: a cross-sectional study from NHANES.Lipids in health and disease · 2024Article
- Causal effects of socioeconomic traits on frailty: a Mendelian randomization study.Frontiers in medicine · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity, birth weight and lifestyle factors have been found associated with the risk of frailty in observational studies, but whether these associations are causal is uncertain. We conducted a two-sample Mendelian randomization study to investigate the associations. Genetic instruments associated with the exposures at the genome-wide significance level (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.