Evidence map›Paper›PMID 38095469›Full record

ArticleMicrobiology spectrum2024

The epidemiology of pediatric outpatient acute respiratory tract infections in the US: a multi-facility analysis of multiplex PCR testing from 2018 to 2023.

Tristan T Timbrook, Margaret Glancey, Brooklyn A Noble, Stephen Eng, Zoe Heins, Benjamin Hommel, Marie Tessonneau, Ben W Galvin, Grace Macalino

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 13 citations in OpenAlex.

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  10. Clinical and prognostic insights into Chlamydia trachomatis in pediatric acute respiratory infections: evidence from targeted next-generation sequencing of 5,021 cases.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Tristan T TimbrookGlobal Medical Affairs, bioMérieux , Salt Lake City, Utah, USA.ORCID 0000-0002-4542-6203
Margaret GlanceyBaker Tilly US, LLP , Philadelphia, Pennsylvania, USA.
Brooklyn A NobleData Science, bioMérieux , Salt Lake City, Utah, USA.
Stephen EngBaker Tilly US, LLP , New York, New York, USA.
Zoe HeinsGlobal Medical Affairs, bioMérieux , Salt Lake City, Utah, USA.
Benjamin HommelGlobal Medical Affairs, bioMérieux , Marcy l'Étoile, France.
Marie TessonneauBaker Tilly US, LLP , New York, New York, USA.
Ben W GalvinData Science, bioMérieux , Salt Lake City, Utah, USA.
Grace MacalinoBaker Tilly , Tysons Corner, Virginia, USA.
bioMérieux (United States) · USBaker Engineering (United States) · USbioMérieux (France) · FRUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importancePost-pandemic, it is essential to understand the epidemiology of pediatric acute respiratory tract infections (ARTIs). Our multi-facility study elucidates the outpatient epidemiology of pediatric ARTI using highly multiplexed PCR testing, providing critical insights into the evolving landscape of the etiological agents with a particular focus on the years following the emergence of SARS-CoV-2. Utilizing data from two different multiplex PCR panels, our research provides a comprehensive analysis of respiratory pathogen positivity from 2018 to 2023. Our findings indicate that over half of the annual test results identified at least one pathogen, primarily of viral origin. Intriguingly, despite the surge in testing during the COVID-19 pandemic, pathogen detection rates remain similar to the pre-pandemic era. These data hold significant implications for directing antimicrobial stewardship strategies, curbing unnecessary antibiotic use in pediatric respiratory diseases, and the value of multiplex PCR testing in the outpatient setting among pediatrics.

Indexed as

OutpatientsRespiratory Tract InfectionsAnti-Bacterial AgentsChildHumansMultiplex Polymerase Chain ReactionPandemicsAnti-Bacterial Agentsantibiotic stewardshipmultiplex PCR testingoutpatient epidemiologypathogen prevalencepediatric respiratory infectionsSARS-CoV-2

Identifiers

PMID38095469
PMCPMC10782947
OpenAlexW4389732650

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.